WormBase Tree Display for Gene: WBGene00000833

WBGene00000833 Evidence: Person_evidence: WBPerson530
  SMap: S_parent: Sequence: T20G5
  Identity: Version: 1
    Name: CGC_name: cts-1 Person_evidence: WBPerson530
      Sequence_name: T20G5.2
      Molecular_name: T20G5.2
        T20G5.2.1
        CE00513
      Other_name: CELE_T20G5.2 Accession_evidence: NDB BX284603
      Public_name: cts-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cts
    Allele (33)
    Strain: WBStrain00001711
      WBStrain00001712
    RNASeq_FPKM (74)
    GO_annotation (19)
    Contained_in_operon: CEOP3660
    Ortholog (45)
    Structured_description: Concise_description: cts-1 encodes a citrate synthase; by homology, CTS-1 is predicted to function in the citric acid cycle to catalyze the formation of citrate from oxaloacetate and acetyl-CoA; cts-1 is required for embryonic development. Paper_evidence: WBPaper00004403
            WBPaper00004424
            WBPaper00005654
          Curator_confirmed: WBPerson567
          Date_last_updated: 26 Oct 2011 00:00:00
      Automated_description: Predicted to enable citrate (Si)-synthase activity. Predicted to be involved in carbohydrate metabolic process and tricarboxylic acid cycle. Located in mitochondrion. Expressed in anal depressor muscle and ventral cord neurons. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and hypertrophic cardiomyopathy. Is an ortholog of human CS (citrate synthase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:11984 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2422)
      DOID:12930 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2422)
  Molecular_info: Corresponding_CDS: T20G5.2
    Corresponding_transcript: T20G5.2.1
    Other_sequence (192)
    Associated_feature (11)
  Experimental_info: RNAi_result (12)
    Expr_pattern: Chronogram1007
      Expr6723
      Expr6724
      Expr1025738
      Expr1030515
      Expr1157217
      Expr2010581
      Expr2028821
    Drives_construct: WBCnstr00002535
      WBCnstr00002536
      WBCnstr00018299
    Microarray_results (19)
    Expression_cluster (147)
    Interaction: WBInteraction000038680
      WBInteraction000041851
      WBInteraction000044231
      WBInteraction000104558
      WBInteraction000106283
      WBInteraction000107396
      WBInteraction000112853
      WBInteraction000113231
      WBInteraction000113232
      WBInteraction000113233
      WBInteraction000113234
      WBInteraction000114643
      WBInteraction000118695
      WBInteraction000124605
      WBInteraction000127410
      WBInteraction000133240
      WBInteraction000133805
      WBInteraction000134702
      WBInteraction000136043
      WBInteraction000136664
      WBInteraction000136757
      WBInteraction000137061
      WBInteraction000137174
      WBInteraction000137774
      WBInteraction000139690
      WBInteraction000140119
      WBInteraction000140200
      WBInteraction000140202
      WBInteraction000141142
      WBInteraction000142249
      WBInteraction000145008
      WBInteraction000145485
      WBInteraction000146286
      WBInteraction000149566
      WBInteraction000151348
      WBInteraction000153141
      WBInteraction000154103
      WBInteraction000155686
      WBInteraction000155879
      WBInteraction000156365
      WBInteraction000156740
      WBInteraction000159878
      WBInteraction000160033
      WBInteraction000168195
      WBInteraction000169741
      WBInteraction000170881
      WBInteraction000175233
      WBInteraction000178602
      WBInteraction000181199
      WBInteraction000182458
      WBInteraction000185280
      WBInteraction000188252
      WBInteraction000194799
      WBInteraction000197340
      WBInteraction000197511
      WBInteraction000197512
      WBInteraction000198047
      WBInteraction000204640
      WBInteraction000206416
      WBInteraction000208340
      WBInteraction000212026
      WBInteraction000212645
      WBInteraction000212782
      WBInteraction000213848
      WBInteraction000220306
      WBInteraction000220954
      WBInteraction000223021
      WBInteraction000223674
      WBInteraction000224956
      WBInteraction000225576
      WBInteraction000225919
      WBInteraction000227448
      WBInteraction000228649
      WBInteraction000230096
      WBInteraction000234716
      WBInteraction000236677
      WBInteraction000240301
      WBInteraction000242444
      WBInteraction000244117
      WBInteraction000244464
      WBInteraction000246171
      WBInteraction000246172
      WBInteraction000247250
      WBInteraction000247649
      WBInteraction000251403
      WBInteraction000253290
      WBInteraction000257075
      WBInteraction000257588
      WBInteraction000257592
      WBInteraction000258697
      WBInteraction000260896
      WBInteraction000261397
      WBInteraction000266195
      WBInteraction000276165
      WBInteraction000278757
      WBInteraction000279073
      WBInteraction000279524
      WBInteraction000282225
      WBInteraction000285351
      WBInteraction000286300
      WBInteraction000293084
      WBInteraction000300596
      WBInteraction000302468
      WBInteraction000303710
      WBInteraction000307518
      WBInteraction000307519
      WBInteraction000307633
      WBInteraction000312134
      WBInteraction000312667
      WBInteraction000321903
      WBInteraction000322835
      WBInteraction000325085
      WBInteraction000327552
      WBInteraction000329500
      WBInteraction000331061
      WBInteraction000331378
      WBInteraction000334711
      WBInteraction000335490
      WBInteraction000338567
      WBInteraction000338839
      WBInteraction000344543
      WBInteraction000348320
      WBInteraction000349614
      WBInteraction000349976
      WBInteraction000353755
      WBInteraction000354012
      WBInteraction000358699
      WBInteraction000364659
      WBInteraction000369725
      WBInteraction000371736
      WBInteraction000372845
      WBInteraction000374971
      WBInteraction000380038
      WBInteraction000381485
      WBInteraction000383094
      WBInteraction000383679
      WBInteraction000385877
      WBInteraction000390023
      WBInteraction000397566
      WBInteraction000398685
      WBInteraction000399048
      WBInteraction000399518
      WBInteraction000408411
      WBInteraction000410523
      WBInteraction000421481
      WBInteraction000432252
      WBInteraction000434622
      WBInteraction000436289
      WBInteraction000436397
      WBInteraction000440055
      WBInteraction000440446
      WBInteraction000441576
      WBInteraction000446528
      WBInteraction000448702
      WBInteraction000450998
      WBInteraction000451289
      WBInteraction000452685
      WBInteraction000454678
      WBInteraction000457423
      WBInteraction000459597
      WBInteraction000460441
      WBInteraction000461349
      WBInteraction000462610
      WBInteraction000462838
      WBInteraction000463804
      WBInteraction000463876
      WBInteraction000464793
      WBInteraction000465849
      WBInteraction000467239
      WBInteraction000467487
      WBInteraction000467488
      WBInteraction000470955
      WBInteraction000474191
      WBInteraction000474734
      WBInteraction000475267
      WBInteraction000475476
      WBInteraction000503560
      WBInteraction000537452
      WBInteraction000537459
      WBInteraction000542385
      WBInteraction000549544
      WBInteraction000551845
      WBInteraction000552676
      WBInteraction000553657
      WBInteraction000554270
      WBInteraction000554371
      WBInteraction000562269
      WBInteraction000562540
      WBInteraction000562911
      WBInteraction000563747
      WBInteraction000568728
      WBInteraction000569417
      WBInteraction000572147
      WBInteraction000572910
      WBInteraction000573384
      WBInteraction000577521
      WBInteraction000579925
      WBInteraction000582013
      WBInteraction000585505
      WBInteraction000586523
  Map_info: Map: III Position: 2.01626 Error: 0.001619
    Positive: Positive_clone: T20G5 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (12)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene