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WormBase Tree Display for Gene: WBGene00000895

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Name Class

WBGene00000895SMapS_parentSequenceB0412
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classdac
Allele (159)
StrainWBStrain00001324
WBStrain00001325
WBStrain00035649
WBStrain00035733
WBStrain00035736
RNASeq_FPKM (74)
GO_annotation00021457
00021458
00021459
00021460
00021461
00021462
00021463
00021464
00021465
Ortholog (36)
Structured_descriptionConcise_descriptiondac-1 encodes the C. elegans ortholog of Dachshund, a transcriptional regulator first described in Drosophila that is a member of the SKI/SNO/DAC family of proteins; dac-1 is expressed at higher levels in the AFD thermosensory neurons as compared to the AWB olfactory neurons and likely plays a role in thermosensory behavior as on thermal gradients dac-1 mutants fail to suppress cryophilic drive but continue to track isotherms at the cultivation temperature; a DAC-1::GFP fusion protein is nuclear and expressed strongly in the AFD thermosensory neurons, but weakly in the AWC, ASE, and ASK chemosensory neurons; expression is also seen in alae and additional, unidentified tail cells; dac-1 expression in AFD is positively regulated by the TTX-1 OTX-like homeodomain protein.Paper_evidenceWBPaper00024671
Curator_confirmedWBPerson1843
Date_last_updated21 May 2007 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in thermotaxis. Located in nucleus. Expressed in amphid neurons; cuticular ala; and tail. Is an ortholog of human DACH1 (dachshund family transcription factor 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSB0412.1a
B0412.1b
Corresponding_CDS_historyB0412.1b:wp120
B0412.1b:wp123
Corresponding_transcriptB0412.1a.1
B0412.1b.1
Other_sequenceDviv_isotig11489
SSC00720_1
Dviv_isotig11488
SS02097
Associated_featureWBsf658584
WBsf978943
WBsf224400
Transcription_factorWBTranscriptionFactor000635
Experimental_infoRNAi_resultWBRNAi00028128Inferred_automaticallyRNAi_primary
WBRNAi00009756Inferred_automaticallyRNAi_primary
WBRNAi00006647Inferred_automaticallyRNAi_primary
WBRNAi00110961Inferred_automaticallyRNAi_primary
WBRNAi00039031Inferred_automaticallyRNAi_primary
Expr_patternChronogram2070
Expr3130
Expr5066
Expr7403
Expr1015167
Expr1143193
Expr1200045
Expr2010758
Expr2028995
Drives_constructWBCnstr00002217
WBCnstr00002218
WBCnstr00011158
WBCnstr00012546
WBCnstr00037214
Construct_productWBCnstr00011158
WBCnstr00016702
WBCnstr00037214
Microarray_results (24)
Expression_cluster (120)
InteractionWBInteraction000029256
WBInteraction000029458
WBInteraction000032720
WBInteraction000032853
WBInteraction000032854
WBInteraction000032882
WBInteraction000034320
WBInteraction000034504
WBInteraction000038405
WBInteraction000040405
WBInteraction000040904
WBInteraction000045536
WBInteraction000045815
WBInteraction000050085
WBInteraction000113433
WBInteraction000169124
WBInteraction000169125
WBInteraction000169126
WBInteraction000173031
WBInteraction000173032
WBInteraction000173033
WBInteraction000322116
WBInteraction000387782
WBInteraction000502028
WBInteraction000514433
WBInteraction000526877
WBInteraction000527939
WBInteraction000528132
WBInteraction000528154
WBInteraction000528222
WBInteraction000528277
WBInteraction000528321
WBInteraction000528363
WBInteraction000528408
WBInteraction000528522
WBInteraction000528531
WBInteraction000528641
WBInteraction000528721
WBInteraction000528802
WBInteraction000528939
WBInteraction000529000
WBInteraction000529040
WBInteraction000529192
WBInteraction000529315
WBInteraction000529420
WBInteraction000529685
WBInteraction000529771
WBInteraction000529789
WBInteraction000530043
WBInteraction000530073
WBInteraction000530099
WBInteraction000530150
WBInteraction000530222
WBInteraction000530410
WBInteraction000530444
WBInteraction000530531
WBInteraction000530730
WBInteraction000530768
WBInteraction000530838
WBInteraction000530887
WBInteraction000531054
WBInteraction000531111
WBInteraction000531192
WBInteraction000531249
WBInteraction000531296
WBInteraction000531695
WBInteraction000531753
WBInteraction000531915
WBInteraction000532026
WBInteraction000532105
WBInteraction000532152
WBInteraction000532200
WBInteraction000532315
WBInteraction000532373
WBInteraction000532395
WBInteraction000532450
WBInteraction000532489
WBInteraction000532585
WBInteraction000532730
WBInteraction000532777
WBInteraction000532824
WBInteraction000532849
WBInteraction000532999
WBInteraction000533073
WBInteraction000533243
WBInteraction000533431
WBInteraction000533675
WBInteraction000533760
WBInteraction000533922
WBInteraction000534144
WBInteraction000534171
WBInteraction000534292
WBInteraction000547016
WBInteraction000547017
WBInteraction000547018
WBProcessWBbiopr:00000010
Map_infoMapIIIPosition-25.7793Error0.003862
PositivePositive_cloneB0412Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4251
Pseudo_map_position
ReferenceWBPaper00010874
WBPaper00024524
WBPaper00024671
WBPaper00026952
WBPaper00027309
WBPaper00033137
WBPaper00034843
WBPaper00038491
WBPaper00055090
WBPaper00065158
Remarkski-1 became an other-name of dac-1 as this locus encodes the C. elegans ortholog of Dachshund, rather than of the related protein SKIPerson_evidenceWBPerson473
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene