WormBase Tree Display for Gene: WBGene00001413

WBGene00001413 SMap: S_parent: Sequence: C01F6
  Identity: Version: 1
    Name: CGC_name: fem-3 Person_evidence: WBPerson261
      Sequence_name: C01F6.4
      Molecular_name: C01F6.4a
        C01F6.4a.1
        CE02953
        C01F6.4c
        CE46813
        C01F6.4b
        C01F6.4c.1
      Other_name: CELE_C01F6.4 Accession_evidence: NDB BX284604
      Public_name: fem-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fem
    Reference_allele: WBVar00144465
      WBVar00240985
    Allele (71)
    Legacy_information: Class 1 (loss-of-function) : e1996sd mat : XO animals transformed into fertile females if mother homozygous e1996 into intersexes if mother heterozygous e1996/+; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. NA > 20 (e1950 e2006ts : XX self-fertile at 20x).
      Class 2 (gain-of-function) : q20sd ts : at 25x XX germline makes only sperm at 15x XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. NA9 (q24 etc. : all ts).
      See also e1950, e1980, e1981, e1983, e1984, e1995, e1996, e1999, e2004, e2006, e2007, e2010, e2043, e2045, e2062, e2063, e2068, e2070, e2143, e2178, e2289, e2353, e2354, e2366
      [C.elegansII] e1996sd,mat,och : XO animals transformed into fertile females if mother homozygous, into intersexes if mother heterozygous; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. OA>20 e1950, e2068amb, e2006ts (XX self-fertile at 20C). Also gf,ts alleles, q20sd,ts (at 25C XX germline makes only sperm, at 15C XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. OA8(gf):q22ts (weaker), q95ts (strongest allele, 80% Mog even at 15C). Cloned: 1.7 kb and 1.55 kb (minor) transcripts, former encodes predicted 388 aa novel protein. gf alleles are alterations in 3'UTR. Transgene overexpression of fem-3 leads to extensive masculinization of XX soma. [Hodgkin 1986; Ahringer et al. 1992; CB; JK; AS]
    Strain (12)
    RNASeq_FPKM (74)
    GO_annotation (26)
    Ortholog (21)
    Structured_description: Concise_description: fem-3 encodes a novel protein that promotes male development in all tissues. Paper_evidence: WBPaper00001378
          Curator_confirmed: WBPerson1843
          Date_last_updated: 11 Apr 2005 00:00:00
      Automated_description: Enables protein phosphatase binding activity. Involved in several processes, including protein localization to chromatin; regulation of reproductive process; and sex determination. Located in cytoplasm and protein-containing complex. Expressed in germ line; spermatid; and in male. Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C01F6.4a
      C01F6.4c
    Corresponding_transcript: C01F6.4b
      C01F6.4a.1
      C01F6.4c.1
    Other_sequence: X64962
      CBC07169_1
    Associated_feature: WBsf660472
      WBsf997355
      WBsf1017925
      WBsf228786
  Experimental_info: RNAi_result: WBRNAi00061018 Inferred_automatically: RNAi_primary
      WBRNAi00030242 Inferred_automatically: RNAi_primary
      WBRNAi00039313 Inferred_automatically: RNAi_primary
      WBRNAi00087453 Inferred_automatically: RNAi_primary
      WBRNAi00007588 Inferred_automatically: RNAi_primary
      WBRNAi00081939 Inferred_automatically: RNAi_primary
      WBRNAi00081938 Inferred_automatically: RNAi_primary
      WBRNAi00085808 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1382
      Expr3829
      Expr9317
      Expr1021877
      Expr1030847
      Expr1143426
      Expr2011751
      Expr2029989
    Drives_construct: WBCnstr00011680
      WBCnstr00018576
      WBCnstr00036963
    Construct_product (17)
    Antibody: WBAntibody00002227
      WBAntibody00002344
    Microarray_results (21)
    Expression_cluster (154)
    Interaction: WBInteraction000000015
      WBInteraction000000037
      WBInteraction000000053
      WBInteraction000000310
      WBInteraction000000463
      WBInteraction000000474
      WBInteraction000000738
      WBInteraction000001109
      WBInteraction000001293
      WBInteraction000001294
      WBInteraction000001305
      WBInteraction000001459
      WBInteraction000001460
      WBInteraction000001584
      WBInteraction000002519
      WBInteraction000002520
      WBInteraction000002521
      WBInteraction000002528
      WBInteraction000002529
      WBInteraction000002530
      WBInteraction000002531
      WBInteraction000002616
      WBInteraction000002812
      WBInteraction000003216
      WBInteraction000003335
      WBInteraction000004898
      WBInteraction000004899
      WBInteraction000004900
      WBInteraction000005385
      WBInteraction000005533
      WBInteraction000005534
      WBInteraction000005666
      WBInteraction000005759
      WBInteraction000008713
      WBInteraction000008729
      WBInteraction000008775
      WBInteraction000028595
      WBInteraction000029015
      WBInteraction000029273
      WBInteraction000029274
      WBInteraction000029275
      WBInteraction000029276
      WBInteraction000030535
      WBInteraction000030543
      WBInteraction000030544
      WBInteraction000030545
      WBInteraction000050596
      WBInteraction000052653
      WBInteraction000052965
      WBInteraction000118186
      WBInteraction000119259
      WBInteraction000120432
      WBInteraction000122459
      WBInteraction000124803
      WBInteraction000126150
      WBInteraction000126151
      WBInteraction000126152
      WBInteraction000126153
      WBInteraction000126551
      WBInteraction000126552
      WBInteraction000127201
      WBInteraction000133590
      WBInteraction000133646
      WBInteraction000134461
      WBInteraction000134969
      WBInteraction000137150
      WBInteraction000138946
      WBInteraction000138979
      WBInteraction000139439
      WBInteraction000140777
      WBInteraction000143114
      WBInteraction000143260
      WBInteraction000143411
      WBInteraction000146672
      WBInteraction000146803
      WBInteraction000146869
      WBInteraction000149514
      WBInteraction000150196
      WBInteraction000150342
      WBInteraction000157102
      WBInteraction000160163
      WBInteraction000161685
      WBInteraction000161770
      WBInteraction000163548
      WBInteraction000163998
      WBInteraction000164073
      WBInteraction000164689
      WBInteraction000165389
      WBInteraction000165801
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      WBInteraction000168794
      WBInteraction000170456
      WBInteraction000170656
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      WBInteraction000176422
      WBInteraction000177473
      WBInteraction000180229
      WBInteraction000180602
      WBInteraction000180983
      WBInteraction000181145
      WBInteraction000181333
      WBInteraction000181389
      WBInteraction000181472
      WBInteraction000181841
      WBInteraction000183089
      WBInteraction000184075
      WBInteraction000186338
      WBInteraction000186416
      WBInteraction000186795
      WBInteraction000187896
      WBInteraction000187903
      WBInteraction000191530
      WBInteraction000191992
      WBInteraction000194321
      WBInteraction000196143
      WBInteraction000197911
      WBInteraction000198796
      WBInteraction000200292
      WBInteraction000200414
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      WBInteraction000203141
      WBInteraction000205595
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      WBInteraction000209776
      WBInteraction000209922
      WBInteraction000209946
      WBInteraction000211216
      WBInteraction000211223
      WBInteraction000211473
      WBInteraction000211494
      WBInteraction000211618
      WBInteraction000211818
      WBInteraction000212300
      WBInteraction000212633
      WBInteraction000212786
      WBInteraction000212900
      WBInteraction000214370
      WBInteraction000214606
      WBInteraction000214788
      WBInteraction000216255
      WBInteraction000216256
      WBInteraction000216512
      WBInteraction000217055
      WBInteraction000217074
      WBInteraction000217792
      WBInteraction000219207
      WBInteraction000219370
      WBInteraction000219750
      WBInteraction000220505
      WBInteraction000221287
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      WBInteraction000222580
      WBInteraction000223220
      WBInteraction000225079
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      WBInteraction000226386
      WBInteraction000226811
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      WBInteraction000230500
      WBInteraction000230775
      WBInteraction000230993
      WBInteraction000231257
      WBInteraction000231651
      WBInteraction000231795
      WBInteraction000232269
      WBInteraction000232646
      WBInteraction000234421
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      WBInteraction000235127
      WBInteraction000235433
      WBInteraction000236341
      WBInteraction000239543
      WBInteraction000243312
      WBInteraction000244447
      WBInteraction000244450
      WBInteraction000247084
      WBInteraction000247140
      WBInteraction000247942
      WBInteraction000248356
      WBInteraction000249068
      WBInteraction000249727
      WBInteraction000249740
      WBInteraction000250614
      WBInteraction000251818
      WBInteraction000252112
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      WBInteraction000254718
      WBInteraction000254987
      WBInteraction000255045
      WBInteraction000255261
      WBInteraction000256467
      WBInteraction000257395
      WBInteraction000259712
      WBInteraction000260572
      WBInteraction000260584
      WBInteraction000263465
      WBInteraction000264053
      WBInteraction000264710
      WBInteraction000265407
      WBInteraction000268672
      WBInteraction000269038
      WBInteraction000269884
      WBInteraction000270186
      WBInteraction000270479
      WBInteraction000271575
      WBInteraction000271914
      WBInteraction000272336
      WBInteraction000273635
      WBInteraction000274286
      WBInteraction000275099
      WBInteraction000277256
      WBInteraction000278710
      WBInteraction000279646
      WBInteraction000281048
      WBInteraction000281642
      WBInteraction000283272
      WBInteraction000284641
      WBInteraction000284642
      WBInteraction000284917
      WBInteraction000285121
      WBInteraction000285873
      WBInteraction000286463
      WBInteraction000287828
      WBInteraction000287903
      WBInteraction000288686
      WBInteraction000289756
      WBInteraction000291853
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      WBInteraction000294837
      WBInteraction000296175
      WBInteraction000296354
      WBInteraction000296960
      WBInteraction000297620
      WBInteraction000300300
      WBInteraction000300953
      WBInteraction000302423
      WBInteraction000302442
      WBInteraction000302983
      WBInteraction000304893
      WBInteraction000307142
      WBInteraction000307542
      WBInteraction000308841
      WBInteraction000309757
      WBInteraction000310415
      WBInteraction000310533
      WBInteraction000310838
      WBInteraction000310865
      WBInteraction000311372
      WBInteraction000311373
      WBInteraction000311669
      WBInteraction000312224
      WBInteraction000312598
      WBInteraction000315091
      WBInteraction000315241
      WBInteraction000316072
      WBInteraction000318433
      WBInteraction000320163
      WBInteraction000322517
      WBInteraction000323702
      WBInteraction000325705
      WBInteraction000327382
      WBInteraction000327879
      WBInteraction000329792
      WBInteraction000330076
      WBInteraction000330079
      WBInteraction000331374
      WBInteraction000333167
      WBInteraction000333849
      WBInteraction000334784
      WBInteraction000335230
      WBInteraction000338682
      WBInteraction000338986
      WBInteraction000344191
      WBInteraction000345043
      WBInteraction000346646
      WBInteraction000347109
      WBInteraction000347187
      WBInteraction000348157
      WBInteraction000349303
      WBInteraction000350645
      WBInteraction000350658
      WBInteraction000351414
      WBInteraction000352358
      WBInteraction000354184
      WBInteraction000354679
      WBInteraction000358461
      WBInteraction000358916
      WBInteraction000359646
      WBInteraction000360241
      WBInteraction000360327
      WBInteraction000360845
      WBInteraction000363693
      WBInteraction000367266
      WBInteraction000368423
      WBInteraction000369089
      WBInteraction000369757
      WBInteraction000370760
      WBInteraction000371278
      WBInteraction000372238
      WBInteraction000372761
      WBInteraction000373900
      WBInteraction000377694
      WBInteraction000378297
      WBInteraction000380455
      WBInteraction000382857
      WBInteraction000383277
      WBInteraction000383706
      WBInteraction000385686
      WBInteraction000387396
      WBInteraction000387586
      WBInteraction000389373
      WBInteraction000389447
      WBInteraction000390234
      WBInteraction000391848
      WBInteraction000394208
      WBInteraction000394728
      WBInteraction000395003
      WBInteraction000397100
      WBInteraction000403437
      WBInteraction000403585
      WBInteraction000403980
      WBInteraction000404498
      WBInteraction000405268
      WBInteraction000406610
      WBInteraction000406871
      WBInteraction000407404
      WBInteraction000408800
      WBInteraction000409307
      WBInteraction000410004
      WBInteraction000410580
      WBInteraction000410958
      WBInteraction000413049
      WBInteraction000414489
      WBInteraction000415115
      WBInteraction000416794
      WBInteraction000417370
      WBInteraction000417793
      WBInteraction000418209
      WBInteraction000418601
      WBInteraction000418677
      WBInteraction000420806
      WBInteraction000422402
      WBInteraction000422999
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      WBInteraction000425176
      WBInteraction000427778
      WBInteraction000432256
      WBInteraction000436384
      WBInteraction000436634
      WBInteraction000437770
      WBInteraction000438260
      WBInteraction000439637
      WBInteraction000444826
      WBInteraction000445290
      WBInteraction000448393
      WBInteraction000451112
      WBInteraction000455044
      WBInteraction000461644
      WBInteraction000461657
      WBInteraction000462312
      WBInteraction000463310
      WBInteraction000465104
      WBInteraction000500323
      WBInteraction000501334
      WBInteraction000502810
      WBInteraction000503024
      WBInteraction000504883
      WBInteraction000504884
      WBInteraction000517740
      WBInteraction000518920
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      WBInteraction000519148
      WBInteraction000519741
      WBInteraction000519742
      WBInteraction000520223
      WBInteraction000520345
      WBInteraction000520691
      WBInteraction000521256
      WBInteraction000521711
      WBInteraction000522695
      WBInteraction000522697
      WBInteraction000523613
      WBInteraction000523614
      WBInteraction000523615
      WBInteraction000523617
      WBInteraction000523619
      WBInteraction000523620
      WBInteraction000524763
      WBInteraction000524774
      WBInteraction000524787
      WBInteraction000524790
      WBInteraction000539981
      WBInteraction000541204
      WBInteraction000541395
      WBInteraction000542719
      WBInteraction000542726
      WBInteraction000542845
      WBInteraction000551350
      WBInteraction000555213
      WBInteraction000555214
      WBInteraction000555215
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      WBInteraction000555217
      WBInteraction000555218
      WBInteraction000555219
      WBInteraction000555220
      WBInteraction000555221
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      WBInteraction000555223
      WBInteraction000555229
      WBInteraction000556052
      WBInteraction000556054
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      WBInteraction000557074
      WBInteraction000557077
      WBInteraction000558239
      WBInteraction000576794
    WBProcess: WBbiopr:00000110
  Map_info: Map: IV Position: 4.04953 Error: 0.001985
    Well_ordered
    Positive: Inside_rearr: eDf18
        eDf19
      Positive_clone: C01F6 Inferred_automatically: From sequence, transcript, pseudogene data
        JK#2
    Mapping_data: 2_point: 1640
      Multi_point (14)
      Pos_neg_data: 959
        964
        972
    Landmark_gene
  Reference (401)
  Picture: WBPicture0000013095
  Method: Gene