WormBase Tree Display for Gene: WBGene00004350
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WBGene00004350 | SMap | S_parent | Sequence | F56B6 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | rgs | |||||
Allele (194) | ||||||
Strain | WBStrain00026370 | |||||
WBStrain00026372 | ||||||
WBStrain00032622 | ||||||
WBStrain00034758 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00021823 | |||||
00021824 | ||||||
00021825 | ||||||
00085200 | ||||||
00085201 | ||||||
Ortholog (38) | ||||||
Paralog (12) | ||||||
Structured_description | Concise_description | rgs-7 encodes three isoforms of an atypical regulator of G protein signaling (RGS) protein that contains both a C2 and an RGS domain, and that binds EGL-30 via both domains, similar in organization to mammalian PDZ-RGS3; the RGS domain has GTPase activator protein (GAP) activity in vitro on mammalian G[alphai]3; RGS-7 thus may stably bind EGL-30 at all stages of EGL-30's GTPase cycle, might organize EGL-30 into a stable multiprotein signalling complex (with GTP[gamma]S), and might persistently inhibit EGL-30 when triggered by calcium or phospholipids; rgs-7 has no obvious function in mass RNAi assays | Paper_evidence | WBPaper00005654 | ||
WBPaper00005958 | ||||||
WBPaper00013066 | ||||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 18 Jun 2007 00:00:00 | |||||
Automated_description | Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | F56B6.2a | ||||
F56B6.2b | ||||||
F56B6.2c | ||||||
F56B6.2e | ||||||
F56B6.2f | ||||||
F56B6.2g | ||||||
F56B6.2h | ||||||
F56B6.2i | ||||||
F56B6.2j | ||||||
Corresponding_CDS_history | F56B6.2d:wp271 | |||||
Corresponding_transcript | F56B6.2a.1 | |||||
F56B6.2b.1 | ||||||
F56B6.2c.1 | ||||||
F56B6.2e.1 | ||||||
F56B6.2f.1 | ||||||
F56B6.2g.1 | ||||||
F56B6.2h.1 | ||||||
F56B6.2i.1 | ||||||
F56B6.2j.1 | ||||||
Other_sequence (21) | ||||||
Associated_feature (27) | ||||||
Experimental_info | RNAi_result | WBRNAi00048645 | Inferred_automatically | RNAi_primary | ||
WBRNAi00048644 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00032932 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00015785 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern (7) | ||||||
Drives_construct | WBCnstr00011142 | |||||
WBCnstr00035547 | ||||||
Construct_product | WBCnstr00011142 | |||||
WBCnstr00035547 | ||||||
Microarray_results (53) | ||||||
Expression_cluster (147) | ||||||
Interaction | WBInteraction000523424 | |||||
WBInteraction000523425 | ||||||
WBInteraction000539245 | ||||||
WBInteraction000543714 | ||||||
WBInteraction000544009 | ||||||
WBInteraction000550677 | ||||||
WBInteraction000550678 | ||||||
WBInteraction000555666 | ||||||
WBInteraction000555672 | ||||||
WBInteraction000556608 | ||||||
WBInteraction000582380 | ||||||
WBProcess | WBbiopr:00000017 | |||||
Map_info (4) | ||||||
Reference (17) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |