WormBase Tree Display for Gene: WBGene00006730
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WBGene00006730 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F39B2 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | uev-1 | Person_evidence | WBPerson89 | |||||
Sequence_name | F39B2.2 | ||||||||
Molecular_name | F39B2.2 | ||||||||
F39B2.2.1 | |||||||||
CE16008 | |||||||||
Other_name | mms-2 | CGC_data_submission | |||||||
CELE_F39B2.2 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | uev-1 | ||||||||
DB_info | Database | AceView | gene | 1P383 | |||||
WormQTL | gene | WBGene00006730 | |||||||
WormFlux | gene | WBGene00006730 | |||||||
NDB | locus_tag | CELE_F39B2.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00006730|UniProtKB=O45495 | |||||||
family | PTHR24068 | ||||||||
NCBI | gene | 173347 | |||||||
RefSeq | protein | NM_061177.6 | |||||||
SwissProt | UniProtAcc | O45495 | |||||||
TREEFAM | TREEFAM_ID | TF316971 | |||||||
UniProt_GCRP | UniProtAcc | O45495 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | uev | ||||||||
Allele (20) | |||||||||
Strain | WBStrain00032660 | ||||||||
WBStrain00037221 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (16) | |||||||||
Contained_in_operon | CEOP1764 | ||||||||
Ortholog (42) | |||||||||
Paralog (18) | |||||||||
Structured_description | Concise_description | uev-1 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the characteristic UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; UEV-1 activity is required cell autonomously for normal trafficking of the GLR-1 glutamate receptor and consequently, for normal locomotory behavior; UEV-1 physically interacts with the UBC-13 ubiquitin conjugating enzyme that is also required for normal locomotory behavior and that is also likely involved in the DNA damage response; a uev-1::gfp reporter fusion is expressed in a wide variety of tissues including the pharynx, neurons, muscle cells, vulva, intestine, distal tip cell, and cells in the anus/tail; UEV-1 reporter fusions localize to nuclei, the cytosol, and ventral cord neurites. | Paper_evidence | WBPaper00005039 | |||||
WBPaper00005337 | |||||||||
WBPaper00037956 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 07 Feb 2011 00:00:00 | ||||||||
Automated_description | Enables ubiquitin conjugating enzyme binding activity. Involved in regulation of locomotion involved in locomotory behavior and regulation of protein localization to cell surface. Located in cytosol; neuron projection; and nucleus. Expressed in several structures, including anus; distal tip cell; germ line; neurons; and ventral nerve cord. Is an ortholog of human UBE2V2 (ubiquitin conjugating enzyme E2 V2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F39B2.2 | |||||||
Corresponding_transcript | F39B2.2.1 | ||||||||
Other_sequence (59) | |||||||||
Associated_feature | WBsf643859 | ||||||||
WBsf657109 | |||||||||
WBsf986228 | |||||||||
WBsf218828 | |||||||||
Experimental_info | RNAi_result | WBRNAi00116884 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00003632 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00046755 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076399 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00082831 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr9183 | ||||||||
Expr9184 | |||||||||
Expr9707 | |||||||||
Expr1010234 | |||||||||
Expr1032806 | |||||||||
Expr1150629 | |||||||||
Expr2017742 | |||||||||
Expr2035881 | |||||||||
Drives_construct | WBCnstr00013774 | ||||||||
Construct_product | WBCnstr00013774 | ||||||||
WBCnstr00013775 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (117) | |||||||||
Interaction | WBInteraction000047993 | ||||||||
WBInteraction000101272 | |||||||||
WBInteraction000111311 | |||||||||
WBInteraction000119040 | |||||||||
WBInteraction000133051 | |||||||||
WBInteraction000134509 | |||||||||
WBInteraction000141403 | |||||||||
WBInteraction000168137 | |||||||||
WBInteraction000168691 | |||||||||
WBInteraction000174597 | |||||||||
WBInteraction000192463 | |||||||||
WBInteraction000194870 | |||||||||
WBInteraction000195942 | |||||||||
WBInteraction000199067 | |||||||||
WBInteraction000206602 | |||||||||
WBInteraction000210365 | |||||||||
WBInteraction000211626 | |||||||||
WBInteraction000213957 | |||||||||
WBInteraction000216009 | |||||||||
WBInteraction000217915 | |||||||||
WBInteraction000217961 | |||||||||
WBInteraction000218149 | |||||||||
WBInteraction000218150 | |||||||||
WBInteraction000218182 | |||||||||
WBInteraction000218224 | |||||||||
WBInteraction000231338 | |||||||||
WBInteraction000265789 | |||||||||
WBInteraction000274019 | |||||||||
WBInteraction000277719 | |||||||||
WBInteraction000312558 | |||||||||
WBInteraction000324609 | |||||||||
WBInteraction000326147 | |||||||||
WBInteraction000360625 | |||||||||
WBInteraction000366495 | |||||||||
WBInteraction000379949 | |||||||||
WBInteraction000391297 | |||||||||
WBInteraction000399212 | |||||||||
WBInteraction000399770 | |||||||||
WBInteraction000411352 | |||||||||
WBInteraction000411999 | |||||||||
WBInteraction000417131 | |||||||||
WBInteraction000429143 | |||||||||
WBInteraction000432732 | |||||||||
WBInteraction000442985 | |||||||||
WBInteraction000457548 | |||||||||
WBInteraction000457608 | |||||||||
WBInteraction000462282 | |||||||||
WBInteraction000465944 | |||||||||
WBInteraction000466447 | |||||||||
WBInteraction000468149 | |||||||||
WBInteraction000468725 | |||||||||
WBInteraction000468781 | |||||||||
WBInteraction000468834 | |||||||||
WBInteraction000469345 | |||||||||
WBInteraction000469553 | |||||||||
WBInteraction000472161 | |||||||||
WBInteraction000472420 | |||||||||
WBInteraction000473106 | |||||||||
WBInteraction000473260 | |||||||||
WBInteraction000475365 | |||||||||
WBInteraction000504733 | |||||||||
WBInteraction000517540 | |||||||||
WBInteraction000517553 | |||||||||
WBInteraction000522375 | |||||||||
WBInteraction000522376 | |||||||||
WBInteraction000522377 | |||||||||
WBInteraction000524674 | |||||||||
WBInteraction000539781 | |||||||||
WBInteraction000539782 | |||||||||
WBInteraction000539783 | |||||||||
WBInteraction000539784 | |||||||||
WBInteraction000539785 | |||||||||
WBInteraction000539786 | |||||||||
WBInteraction000539787 | |||||||||
WBInteraction000539788 | |||||||||
WBInteraction000539795 | |||||||||
WBInteraction000539923 | |||||||||
WBInteraction000539924 | |||||||||
WBInteraction000550866 | |||||||||
WBInteraction000550867 | |||||||||
WBInteraction000550868 | |||||||||
WBInteraction000550869 | |||||||||
WBInteraction000550870 | |||||||||
WBInteraction000550871 | |||||||||
WBInteraction000550872 | |||||||||
WBInteraction000554508 | |||||||||
WBInteraction000555300 | |||||||||
WBInteraction000555953 | |||||||||
WBInteraction000556833 | |||||||||
WBInteraction000558946 | |||||||||
WBInteraction000567887 | |||||||||
WBInteraction000580476 | |||||||||
WBInteraction000584937 | |||||||||
Map_info | Map | I | Position | 26.8835 | Error | 0.138356 | |||
Positive | Positive_clone | F39B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4669 | |||||||
Pseudo_map_position | |||||||||
Reference (16) | |||||||||
Remark | Sequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb | ||||||||
Sequence connection from [Boulton S, Vidal M] | |||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |