snfc-5 encodes a homolog of SNF5/Ini1, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; snfc-5 may be involved in asymmetric cell division of the T cells.
Predicted to enable transcription coactivator activity. Predicted to be involved in chromatin remodeling and positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of brahma complex; nBAF complex; and npBAF complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); central nervous system cancer (multiple); and connective tissue cancer (multiple). Is an ortholog of human SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.