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WormBase Tree Display for Gene: WBGene00022199

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Name Class

WBGene00022199SMapS_parentSequenceY71H10A
IdentityVersion3
NameCGC_namepfk-1.1Person_evidenceWBPerson3194
Sequence_nameY71H10A.1
Molecular_nameY71H10A.1a
Y71H10A.1a.1
CE28266
Y71H10A.1b
Other_namepfk-1Person_evidenceWBPerson261
CELE_Y71H10A.1Accession_evidenceNDBBX284606
Public_namepfk-1.1
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
228 Sep 2012 14:29:00WBPerson2970Name_changeCGC_namepfk-1
303 Mar 2014 14:12:13WBPerson2970Name_changeCGC_namepfk-1.1
Other_namepfk-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpfk
Allele (73)
RNASeq_FPKM (74)
GO_annotation (33)
Ortholog (58)
ParalogWBGene00008230Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpfk-1.1 encodes two isoforms of a 6-phosphofructokinase (E.C. 2.7.1.11), paralogous to PFK-1.2; pfk-1.1 is an essential gene, and expressed in proximal germline and in several larval and adult tissues (including neurons, hypodermis, and pharyngeal muscle).Paper_evidenceWBPaper00004651
WBPaper00005654
WBPaper00025054
WBPaper00027758
WBPaper00028588
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated24 Feb 2014 00:00:00
Automated_descriptionPredicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Expressed in germ line; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type) and PFKM (phosphofructokinase, muscle).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:11721Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8877)
Molecular_infoCorresponding_CDSY71H10A.1a
Corresponding_CDS_historyY71H10A.1b:wp129
Y71H10A.1b:wp245
Corresponding_transcriptY71H10A.1b
Y71H10A.1a.1
Other_sequence (124)
Associated_featureWBsf718535
WBsf1004484
WBsf235423
WBsf235424
WBsf235425
Experimental_infoRNAi_resultWBRNAi00021365Inferred_automaticallyRNAi_primary
WBRNAi00001724Inferred_automaticallyRNAi_primary
WBRNAi00037787Inferred_automaticallyRNAi_primary
WBRNAi00058226Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00023148
WBCnstr00042042
Construct_productWBCnstr00042042
Microarray_results (31)
Expression_cluster (162)
InteractionWBInteraction000042711
WBInteraction000043122
WBInteraction000043997
WBInteraction000044246
WBInteraction000045828
WBInteraction000046145
WBInteraction000046693
WBInteraction000046990
WBInteraction000046994
WBInteraction000047561
WBInteraction000047565
WBInteraction000047566
WBInteraction000047568
WBInteraction000112560
WBInteraction000118827
WBInteraction000138136
WBInteraction000143550
WBInteraction000146946
WBInteraction000152487
WBInteraction000155685
WBInteraction000156505
WBInteraction000158013
WBInteraction000158016
WBInteraction000158387
WBInteraction000158393
WBInteraction000158840
WBInteraction000158955
WBInteraction000159141
WBInteraction000159222
WBInteraction000159269
WBInteraction000159402
WBInteraction000163855
WBInteraction000166783
WBInteraction000174221
WBInteraction000193992
WBInteraction000239693
WBInteraction000243940
WBInteraction000255986
WBInteraction000260517
WBInteraction000266731
WBInteraction000269446
WBInteraction000288915
WBInteraction000309765
WBInteraction000313032
WBInteraction000336044
WBInteraction000345473
WBInteraction000356339
WBInteraction000358800
WBInteraction000361750
WBInteraction000364421
WBInteraction000366700
WBInteraction000367685
WBInteraction000379136
WBInteraction000387740
WBInteraction000387762
WBInteraction000387921
WBInteraction000388074
WBInteraction000388137
WBInteraction000388358
WBInteraction000388359
WBInteraction000398430
WBInteraction000400399
WBInteraction000401210
WBInteraction000406543
WBInteraction000420203
WBInteraction000424550
WBInteraction000432317
WBInteraction000441160
WBInteraction000449655
WBInteraction000461478
WBInteraction000464385
WBInteraction000464983
WBInteraction000466259
WBInteraction000466485
WBInteraction000469092
WBInteraction000469804
WBInteraction000472486
WBInteraction000474126
WBInteraction000474411
WBInteraction000550135
WBInteraction000562916
WBInteraction000569547
WBInteraction000569548
WBInteraction000571852
WBInteraction000574869
WBInteraction000578207
WBInteraction000578545
WBInteraction000579631
WBInteraction000581267
WBInteraction000582848
WBInteraction000584912
WBInteraction000586800
Map_infoMapXPosition-12.6701
PositivePositive_cloneY71H10AInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (16)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene