WormBase Tree Display for Gene: WBGene00006762
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WBGene00006762 | SMap | S_parent | Sequence | Y37D8A | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info (12) | |||||||
Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00045914 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 06 Jun 2019 00:00:00 | ||||||
DOID:1826 | Homo sapiens | Paper_evidence | WBPaper00035198 | ||||
Curator_confirmed | WBPerson38202 | ||||||
Date_last_updated | 04 Jun 2018 00:00:00 | ||||||
DOID:0050669 | Homo sapiens | Paper_evidence | WBPaper00024523 | ||||
Accession_evidence | OMIM | 603513 | |||||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 22 Apr 2013 00:00:00 | ||||||
Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092) | |||
DOID:3312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092) | ||||
DOID:670 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092,HGNC:4093) | ||||
DOID:11714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4093) | ||||
DOID:0060001 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092) | ||||
DOID:9744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4093) | ||||
DOID:1742 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092,HGNC:4093) | ||||
DOID:2030 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092) | ||||
DOID:9976 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092,HGNC:4093) | ||||
DOID:0050741 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092,HGNC:4093) | ||||
DOID:0112223 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092) | ||||
DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4092,HGNC:4093) | ||||
Disease_relevance | Mutations in Glutamic acid decarboxylase (GAD1), the human ortholog of elegans unc-25, are associated with autosomal recessive spastic cerebral palsy, a movement disorder caused by abnormalities in the brain; studies in elegans show that unc-25 is required for gamma-amino-butyric acid (GABA) synthesis and GABA-mediated behavioral functions; various GABA mutants in elegans, like unc-25, the GABA vesicular transporters (unc-46 and unc-47), and the GABA-A receptor, unc-49, all present head-bobbing convulsions. | Homo sapiens | Paper_evidence | WBPaper00024523 | |||
WBPaper00042136 | |||||||
Accession_evidence | OMIM | 603513 | |||||
605363 | |||||||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 22 Apr 2013 00:00:00 | ||||||
Models_disease_in_annotation | WBDOannot00000163 | ||||||
Models_disease_asserted | WBDOannot00000549 | ||||||
WBDOannot00000702 | |||||||
WBDOannot00000703 | |||||||
Molecular_info | Corresponding_CDS | Y37D8A.23a | |||||
Y37D8A.23b | |||||||
Y37D8A.23c | |||||||
Corresponding_transcript | Y37D8A.23a.1 | ||||||
Y37D8A.23b.1 | |||||||
Y37D8A.23c.1 | |||||||
Other_sequence (65) | |||||||
Associated_feature | WBsf645681 | ||||||
WBsf994764 | |||||||
WBsf994765 | |||||||
WBsf1016280 | |||||||
WBsf1016281 | |||||||
WBsf1016282 | |||||||
WBsf225951 | |||||||
WBsf225952 | |||||||
Experimental_info | RNAi_result | WBRNAi00090105 | Inferred_automatically | RNAi_primary | |||
WBRNAi00077589 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00077586 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00027872 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089945 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00002293 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00055883 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00090263 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089782 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (15) | |||||||
Drives_construct (136) | |||||||
Construct_product | WBCnstr00010179 | ||||||
WBCnstr00038179 | |||||||
WBCnstr00038181 | |||||||
Regulate_expr_cluster | WBPaper00065734:unc-25(e156)_downregulated | ||||||
WBPaper00065734:unc-25(e156)_upregulated | |||||||
Microarray_results (30) | |||||||
Expression_cluster (186) | |||||||
Interaction (55) | |||||||
WBProcess | WBbiopr:00000010 | ||||||
Map_info | Map | III | Position | 20.6616 | Error | 0.04207 | |
Well_ordered | |||||||
Positive | Positive_clone | Y37D8A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | 2_point | 57 | |||||
68 | |||||||
78 | |||||||
6019 | |||||||
6109 | |||||||
7009 | |||||||
7010 | |||||||
Multi_point | 93 | ||||||
854 | |||||||
1077 | |||||||
1505 | |||||||
1658 | |||||||
1659 | |||||||
1661 | |||||||
2027 | |||||||
2028 | |||||||
2033 | |||||||
2111 | |||||||
2115 | |||||||
2116 | |||||||
2117 | |||||||
2118 | |||||||
2119 | |||||||
2120 | |||||||
2122 | |||||||
2212 | |||||||
2236 | |||||||
2249 | |||||||
2250 | |||||||
3053 | |||||||
3054 | |||||||
3055 | |||||||
3056 | |||||||
3057 | |||||||
3108 | |||||||
3114 | |||||||
3236 | |||||||
3248 | |||||||
3262 | |||||||
3263 | |||||||
3264 | |||||||
3266 | |||||||
3439 | |||||||
3440 | |||||||
3536 | |||||||
3545 | |||||||
3546 | |||||||
3904 | |||||||
4675 | |||||||
Pos_neg_data | 354 | ||||||
8378 | |||||||
8386 | |||||||
8389 | |||||||
8550 | |||||||
Reference (216) | |||||||
Method | Gene |