Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00002069

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00002069SMapS_parentSequenceC04F12
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classikb
Allele (53)
Possibly_affected_byWBVar02153293
StrainWBStrain00029112
WBStrain00051604
WBStrain00051846
RNASeq_FPKM (74)
GO_annotation00018666
00018667
00018668
00018669
00018670
00018671
00018672
00018673
00109966
OrthologWBGene00026561Caenorhabditis briggsaeFrom_analysisHillier-set
OrthoMCL
OMA
Inparanoid_8
WormBase-Compara
WBGene00150914Caenorhabditis brenneriFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00155925Caenorhabditis brenneriFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00079816Caenorhabditis remaneiFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00125463Caenorhabditis japonicaFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
WBGene00092856Pristionchus pacificusFrom_analysisInparanoid_8
CBOVI.g12259Caenorhabditis bovisFrom_analysisWormBase-Compara
CSP26.g14160Caenorhabditis zanzibariFrom_analysisWormBase-Compara
CSP28.g7775Caenorhabditis panamensisFrom_analysisWormBase-Compara
CSP29.g13509Caenorhabditis beceiFrom_analysisWormBase-Compara
CSP31.g596Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP32.g8019Caenorhabditis sulstoniFrom_analysisWormBase-Compara
CSP38.g11537Caenorhabditis quiockensisFrom_analysisWormBase-Compara
CSP39.g977Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP40.g20217Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Cni-ikb-1Caenorhabditis nigoniFrom_analysisWormBase-Compara
Csp11.Scaffold629.g15291Caenorhabditis tropicalisFrom_analysisWormBase-Compara
Csp5_scaffold_00511.g12307Caenorhabditis sinicaFrom_analysisWormBase-Compara
FL83_11648Caenorhabditis latensFrom_analysisWormBase-Compara
GCK72_000575Caenorhabditis remaneiFrom_analysisWormBase-Compara
OTIPU.nOt.2.0.1.g10458Oscheius tipulaeFrom_analysisWormBase-Compara
Pan_g20449Panagrellus redivivusFrom_analysisWormBase-Compara
Sp34_10059600Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrI_pilon.g1882Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00089701Pristionchus pacificusFrom_analysisWormBase-Compara
WBGene00275371Pristionchus pacificusFrom_analysisWormBase-Compara
HGNC:7795Homo sapiensFrom_analysisOrthoFinder
OrthoInspector
PhylomeDB
MGI:88140Mus musculusFrom_analysisOrthoInspector
Panther
MGI:97312Mus musculusFrom_analysisOrthoFinder
OrthoInspector
MGI:1099800Mus musculusFrom_analysisOrthoFinder
OrthoInspector
MGI:1194908Mus musculusFrom_analysisOrthoInspector
Panther
MGI:1918202Mus musculusFrom_analysisInparanoid
Panther
RGD:70498Rattus norvegicusFrom_analysisOrthoFinder
OrthoInspector
PhylomeDB
ParalogWBGene00006780Caenorhabditis elegansFrom_analysisPanther
WBGene00012124Caenorhabditis elegansFrom_analysisPanther
WBGene00011240Caenorhabditis elegansFrom_analysisPanther
WBGene00007252Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionikb-1 encodes an ortholog of human BCL3 (OMIM:109560) that physically interacts with the checkpoint protein MRT-2; ikb-1(nr2019) and ikb-1(nr2027) mutants display no obvious phenotype other than shortened lifespan; mutation of BCL3 is frequently associated with recurring translocations found in the neoplastic cells of patients with chronic lymphocytic leukemia, and has been implicated in cell cycle control (perhaps via apoptosis).Paper_evidenceWBPaper00004589
WBPaper00004692
WBPaper00005039
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable NF-kappaB binding activity. Involved in defense response to Gram-negative bacterium. Located in cytoplasm. Human ortholog(s) of this gene implicated in common variable immunodeficiency 10. Is an ortholog of human NFKB2 (nuclear factor kappa B subunit 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0081152Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7795)
Molecular_infoCorresponding_CDSC04F12.3
Corresponding_transcriptC04F12.3.1
Other_sequence (38)
Associated_featureWBsf643607
WBsf643608
WBsf656781
WBsf984774
WBsf984775
WBsf1010411
WBsf1010412
WBsf218325
Experimental_infoRNAi_resultWBRNAi00002902Inferred_automaticallyRNAi_primary
WBRNAi00114630Inferred_automaticallyRNAi_primary
WBRNAi00028440Inferred_automaticallyRNAi_primary
WBRNAi00039630Inferred_automaticallyRNAi_primary
WBRNAi00091427Inferred_automaticallyRNAi_primary
WBRNAi00075903Inferred_automaticallyRNAi_primary
WBRNAi00067972Inferred_automaticallyRNAi_primary
WBRNAi00001332Inferred_automaticallyRNAi_primary
Expr_patternExpr9563
Expr15289
Expr1026817
Expr1031222
Expr1143726
Expr2012714
Expr2030950
Drives_constructWBCnstr00036478
Construct_productWBCnstr00014128
WBCnstr00036478
Regulate_expr_clusterWBPaper00060445:ikb-1(nr2027)_downregulated_L1
WBPaper00060445:ikb-1(nr2027)_downregulated_L4
WBPaper00060445:ikb-1(nr2027)_upregulated_L1
WBPaper00060445:ikb-1(nr2027)_upregulated_L4
WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_downregulated_L4
WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
Microarray_results (19)
Expression_cluster (210)
Interaction (127)
WBProcessWBbiopr:00000039
Map_infoMapIPosition3.85381Error0.000485
PositivePositive_cloneC04F12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4781
Pseudo_map_position
Reference (18)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene