WormBase Tree Display for Gene: WBGene00007698

WBGene00007698 SMap: S_parent: Sequence: C24F3
  Identity: Version: 2
    Name: CGC_name: qns-1 Paper_evidence: WBPaper00037116
      Sequence_name: C24F3.4
      Molecular_name: C24F3.4a
        C24F3.4a.1
        CE18521
        C24F3.4b
        CE46056
        C24F3.4c
        CE45996
        C24F3.4b.1
        C24F3.4c.1
      Other_name: CELE_C24F3.4 Accession_evidence: NDB BX284604
      Public_name: qns-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 14 Sep 2010 16:06:52 WBPerson2970 Name_change: CGC_name: qns-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: qns
    Allele (53)
    Strain: WBStrain00051003
      WBStrain00051228
    RNASeq_FPKM (74)
    GO_annotation (22)
    Contained_in_operon: CEOP4364
    Ortholog: WBGene00026262 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00073359 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00162466 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00152928 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00084136 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
      WBGene00124659 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00127017 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00065667 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00092814 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      CBOVI.g8355 Caenorhabditis bovis From_analysis: WormBase-Compara
      CBOVI.g8357 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3625 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g7084 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g7086 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g2502 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP28.g2504 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22077 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP29.g22079 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g13665 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g13667 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9172 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP32.g9174 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g20711 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g20713 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g5496 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g8356 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g13103 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_01060.g15535 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-qns-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Cnig_chr_IV.g14304 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold585.g4770 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00369.g10288 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_00369.g10290 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04758 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014354 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_014356 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g12446 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g12448 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g4713 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40259400 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11537 Caenorhabditis elegans From_analysis: WormBase-Compara
      chrIV_pilon.g11539 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00264412 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00289680 Trichuris muris From_analysis: WormBase-Compara
      WBGene00296631 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001116 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0030512 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-070615-22 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:29832 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1926164 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:727801 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: qns-1 encodes an NAD+ synthase orthologous to human NAD synthetase 1 (HGNC:NADSYN1); by homology, QNS-1 is predicted to catalyze the final step in NAD+ synthesis; loss of qns-1 activity via RNAi results in reduced NAD+ levels and shortened adult lifespan. Paper_evidence: WBPaper00043942
          Curator_confirmed: WBPerson1843
            WBPerson324
          Date_last_updated: 14 Nov 2014 00:00:00
      Automated_description: Enables NAD+ synthase activity. Involved in NAD biosynthetic process and determination of adult lifespan. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human NADSYN1 (NAD synthetase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3070 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29832)
      EFO:MONDO:0020831 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29832)
  Molecular_info: Corresponding_CDS: C24F3.4a
      C24F3.4b
      C24F3.4c
    Corresponding_transcript: C24F3.4a.1
      C24F3.4b.1
      C24F3.4c.1
    Other_sequence (36)
    Associated_feature: WBsf230695
  Experimental_info: RNAi_result: WBRNAi00029149 Inferred_automatically: RNAi_primary
      WBRNAi00069439 Inferred_automatically: RNAi_primary
      WBRNAi00011113 Inferred_automatically: RNAi_primary
      WBRNAi00062132 Inferred_automatically: RNAi_primary
      WBRNAi00041094 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1017165
      Expr1033329
      Expr1145131
      Expr2015210
      Expr2033444
    Microarray_results (23)
    Expression_cluster (84)
    Interaction (44)
  Map_info: Map: IV Position: 4.56087
    Positive: Positive_clone: C24F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00036109
    WBPaper00038491
    WBPaper00043942
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene