WormBase Tree Display for Gene: WBGene00007993

WBGene00007993 SMap: S_parent: Sequence: C37E2
  Identity: Version: 2
    Name: CGC_name: idhb-1 Person_evidence: WBPerson1983
            WBPerson261
      Sequence_name: C37E2.1
      Molecular_name: C37E2.1
        C37E2.1.1
        CE08620
        C37E2.1.2
      Other_name: CELE_C37E2.1 Accession_evidence: NDB BX284606
      Public_name: idhb-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Dec 2011 12:14:43 WBPerson2970 Name_change: CGC_name: idhb-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: idhb
    Allele (85)
    Strain: WBStrain00001632
      WBStrain00003080
      WBStrain00032521
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog: WBGene00069509 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00036287 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00145154 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00134562 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00111219 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00222910 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g3654 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g14066 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g9928 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g13486 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g20653 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g24615 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g728 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g18499 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g19352 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g1113 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00446.g10944 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-idhb-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold628.g7097 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01911.g23839 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_03807.g31293 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_15307 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_022586 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g01313 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g19465 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0028400 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g20534 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239114 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00264565 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00264567 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00294241 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000004982 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0038922 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040625-174 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:5385 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2158650 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:621881 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00009440 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016266 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009664 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: C37E2.1 encodes the C. elegans homolog of the beta subunit of an NAD+-dependent mitochondrial isocitrate dehydrogenase; by homology, the product of C37E2.1 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate as part of the citric acid cycle. Curator_confirmed: WBPerson1843
          Date_last_updated: 26 Oct 2011 00:00:00
      Automated_description: Predicted to enable isocitrate dehydrogenase (NAD+) activity and metal ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in retinitis pigmentosa 46. Is an ortholog of human IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110409 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5385)
  Molecular_info: Corresponding_CDS: C37E2.1
    Corresponding_transcript: C37E2.1.1
      C37E2.1.2
    Other_sequence (88)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00093933 Inferred_automatically: RNAi_primary
      WBRNAi00029640 Inferred_automatically: RNAi_primary
      WBRNAi00070695 Inferred_automatically: RNAi_primary
      WBRNAi00093903 Inferred_automatically: RNAi_primary
      WBRNAi00011720 Inferred_automatically: RNAi_primary
      WBRNAi00093973 Inferred_automatically: RNAi_primary
      WBRNAi00070696 Inferred_automatically: RNAi_primary
      WBRNAi00042113 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1762
      Chronogram1864
      Expr5463
      Expr1011002
      Expr1033477
      Expr1146114
      Expr2012672
      Expr2030908
    Drives_construct: WBCnstr00002471
      WBCnstr00004352
      WBCnstr00033325
    Construct_product: WBCnstr00033325
    Microarray_results (25)
    Expression_cluster (147)
    Interaction (71)
  Map_info: Map: X Position: 16.6584
    Positive: Positive_clone: C37E2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027145
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00065625
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene