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WormBase Tree Display for Gene: WBGene00010305

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Name Class

WBGene00010305SMapS_parentSequenceF59A2
IdentityVersion1
NameSequence_nameF59A2.5
Molecular_nameF59A2.5
F59A2.5.1
CE01023
Other_nameCELE_F59A2.5Accession_evidenceNDBBX284603
Public_nameF59A2.5
DB_infoDatabaseAceViewgene3E495
WormQTLgeneWBGene00010305
WormFluxgeneWBGene00010305
NDBlocus_tagCELE_F59A2.5
PanthergeneCAEEL|WormBase=WBGene00010305|UniProtKB=Q21019
familyPTHR31283
NCBIgene175444
RefSeqproteinNM_065303.4
TrEMBLUniProtAccQ21019
UniProt_GCRPUniProtAccQ21019
OMIMgene300060
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
AlleleWBVar01500082
WBVar01498832
WBVar01500142
WBVar01500143
WBVar00393972
WBVar00393973
WBVar00815592
WBVar00259028
WBVar01606973
RNASeq_FPKM (74)
GO_annotation00070016
00070017
Contained_in_operonCEOP3112
OrthologWBGene00031380Caenorhabditis briggsaeFrom_analysisHillier-set
OrthoMCL
OMA
Inparanoid_8
WormBase-Compara
WBGene00054865Caenorhabditis remaneiFrom_analysisOMA
Inparanoid_8
WormBase-Compara
WBGene00131702Caenorhabditis japonicaFrom_analysisOMA
Inparanoid_8
WormBase-Compara
WBGene00219336Caenorhabditis brenneriFrom_analysisWormBase-Compara
CSP26.g20222Caenorhabditis zanzibariFrom_analysisWormBase-Compara
CSP28.g16304Caenorhabditis panamensisFrom_analysisWormBase-Compara
CSP29.g6787Caenorhabditis beceiFrom_analysisWormBase-Compara
CSP31.g15562Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP32.g6500Caenorhabditis sulstoniFrom_analysisWormBase-Compara
CSP38.g5511Caenorhabditis quiockensisFrom_analysisWormBase-Compara
CSP39.g8620Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP40.g8129Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Cang_2012_03_13_00212.g7122Caenorhabditis angariaFrom_analysisWormBase-Compara
Cni-F59A2.5Caenorhabditis nigoniFrom_analysisWormBase-Compara
Csp11.Scaffold629.g9463Caenorhabditis tropicalisFrom_analysisWormBase-Compara
Csp5_scaffold_00121.g4903Caenorhabditis sinicaFrom_analysisWormBase-Compara
FL83_10311Caenorhabditis latensFrom_analysisWormBase-Compara
GCK72_009675Caenorhabditis remaneiFrom_analysisWormBase-Compara
Sp34_30217710Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrIII_pilon.g7245Caenorhabditis elegansFrom_analysisWormBase-Compara
SGD:S000028512Saccharomyces cerevisiaeFrom_analysisOrthoFinder
Panther
FB:FBgn0260224Drosophila melanogasterFrom_analysisOrthoFinder
Panther
PhylomeDB
HGNC:26058Homo sapiensFrom_analysisOrthoFinder
Panther
MGI:1913442Mus musculusFrom_analysisOrthoFinder
Panther
MGI:1917312Mus musculusFrom_analysisOrthoFinder
Panther
MGI:3644285Mus musculusFrom_analysisOrthoFinder
Panther
MGI:3645826Mus musculusFrom_analysisOrthoFinder
Panther
RGD:1562476Rattus norvegicusFrom_analysisOrthoFinder
Panther
RGD:1561702Rattus norvegicusFrom_analysisOrthoFinder
Panther
RGD:1597340Rattus norvegicusFrom_analysisOrthoFinder
Panther
RGD:7585162Rattus norvegicusFrom_analysisOrthoFinder
Panther
Structured_descriptionConcise_descriptionF59A2.5 encodes a moderately small (123-residue) protein; F59A2.5 isorthologous to Brugia 14979.m04575, and more distantly similar tobudding yeast Pcc1p, to human CTAG1B (OMIM:300156, cancer antigen),CTAG2 (OMIM:300396, melanoma antigen), and LAGE3 (OMIM:300060), and tomany other uncharacterized proteins, ~80-200 residues long, in animals,fungi, and plants; F59A2.5 is required for fertility and embryonicdevelopment in mass RNAi assays and is bound by CKU-80 in two-hybridassays; F59A2.5 is transcriptionally activated by HLH-2 and HLH-8, buthas no known expression pattern; while F59A2.5 is putatively secretedand its human homologs are antigens, its yeast homolog Pcc1p is thoughtto be a transcription factor.Paper_evidenceWBPaper00005039
WBPaper00005654
WBPaper00024925
WBPaper00025054
WBPaper00027104
WBPaper00029286
Curator_confirmedWBPerson567
Date_last_updated02 May 2007 00:00:00
Automated_descriptionPredicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 2. Is an ortholog of human LAGE3 (L antigen family member 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080244Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:26058)
Molecular_infoCorresponding_CDSF59A2.5
Corresponding_transcriptF59A2.5.1
Other_sequenceCBC17030_1
CJC16429_1
Associated_featureWBsf645024
WBsf645025
WBsf645026
WBsf658747
WBsf224609
Experimental_infoRNAi_resultWBRNAi00033156Inferred_automaticallyRNAi_primary
WBRNAi00061484Inferred_automaticallyRNAi_primary
WBRNAi00067660Inferred_automaticallyRNAi_primary
WBRNAi00049097Inferred_automaticallyRNAi_primary
WBRNAi00016048Inferred_automaticallyRNAi_primary
WBRNAi00006784Inferred_automaticallyRNAi_primary
Expr_patternChronogram635
Expr3904
Expr1025290
Expr1034496
Expr1152838
Expr2004434
Expr2022656
Drives_constructWBCnstr00002760
WBCnstr00011737
Microarray_results (19)
Expression_cluster (100)
Interaction (53)
Map_infoPositivePositive_cloneF59A2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIII-6.97262
ReferenceWBPaper00042178
MethodGene