WormBase Tree Display for Gene: WBGene00010671

WBGene00010671 SMap: S_parent: Sequence: K08E7
  Identity: Version: 2
    Name: CGC_name: eak-7 Person_evidence: WBPerson545
            WBPerson272
      Sequence_name: K08E7.1
      Molecular_name: K08E7.1
        K08E7.1.1
        CE11920
      Other_name: CELE_K08E7.1 Accession_evidence: NDB BX284604
      Public_name: eak-7
    DB_info: Database: AceView gene 4N328
            4N330
        WormQTL gene WBGene00010671
        WormFlux gene WBGene00010671
        NDB locus_tag CELE_K08E7.1
        Panther gene CAEEL|WormBase=WBGene00010671|UniProtKB=Q21342
          family PTHR23354
        NCBI gene 3564920
        RefSeq protein NM_070004.7
        TREEFAM TREEFAM_ID TF316541
        TrEMBL UniProtAcc Q21342
        UniProt_GCRP UniProtAcc Q21342
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 18 May 2010 11:51:00 WBPerson2970 Name_change: CGC_name: eak-7
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: eak
    Allele (33)
    Strain: WBStrain00001693
      WBStrain00003892
    RNASeq_FPKM (74)
    GO_annotation: 00071347
      00071348
    Contained_in_operon: CEOP4520
    Ortholog: WBGene00034265 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00072008 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00164490 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00133918 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00089903 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00225182 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g9397 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5067 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g14309 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g2617 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22185 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g7586 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g14015 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13503 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g164 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g23926 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-eak-7 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g10660 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00024.g1439 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_12098 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_016208 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g05718 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40031500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_40031810 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_40032110 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12109 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248508 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00275442 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00306067 Pristionchus pacificus From_analysis: WormBase-Compara
      FB:FBgn0031904 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050419-140 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:29325 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1921597 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1308461 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00018700 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021442 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: eak-7 encodes a conserved protein that contains a TLDc (TBC and LysM domain-containing) domain and an N-myristoylation motif; EAK-7 negatively regulates dauer formation and longevity by controlling the nuclear activity of the DAF-16/FoxO transcription factor; an EAK-7::GFP is widely expressed and localizes to the plasma membrane. Paper_evidence: WBPaper00036472
          Curator_confirmed: WBPerson1843
          Date_last_updated: 28 Nov 2011 00:00:00
      Automated_description: Located in plasma membrane. Expressed in body wall musculature; hypodermis; pharynx; and vulva. Is an ortholog of human MEAK7 (MTOR associated protein, eak-7 homolog). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K08E7.1
    Corresponding_transcript: K08E7.1.1
    Other_sequence (17)
    Associated_feature: WBsf034302
      WBsf998159
      WBsf998160
      WBsf1018390
      WBsf1018391
      WBsf231037
      WBsf231038
  Experimental_info: RNAi_result: WBRNAi00090647 Inferred_automatically: RNAi_primary
      WBRNAi00050302 Inferred_automatically: RNAi_primary
      WBRNAi00008173 Inferred_automatically: RNAi_primary
      WBRNAi00034142 Inferred_automatically: RNAi_primary
      WBRNAi00016814 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6365
      Expr9082
      Expr9089
      Expr1010878
      Expr1034667
      Expr1154004
      Expr2011149
      Expr2029385
    Drives_construct: WBCnstr00002517
      WBCnstr00031235
    Construct_product: WBCnstr00007250
      WBCnstr00007251
      WBCnstr00007252
      WBCnstr00007253
      WBCnstr00007254
      WBCnstr00013708
      WBCnstr00013714
      WBCnstr00031235
    Microarray_results (21)
    Expression_cluster (81)
    Interaction (28)
    Anatomy_function: WBbtf0393
      WBbtf0394
      WBbtf0395
      WBbtf0396
      WBbtf0397
      WBbtf0398
    WBProcess: WBbiopr:00000001
  Map_info: Map: IV Position: 6.02266
    Positive: Positive_clone: K08E7 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene