WormBase Tree Display for Gene: WBGene00011867

WBGene00011867 SMap: S_parent: Sequence: T20G5
  Identity: Version: 3
    Name: CGC_name: chc-1 Person_evidence: WBPerson217
      Sequence_name: T20G5.1
      Molecular_name: T20G5.1
        T20G5.1.1
        CE00480
      Other_name: clhc-1 Paper_evidence: WBPaper00031805
        CELE_T20G5.1 Accession_evidence: NDB BX284603
      Public_name: chc-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Nov 2004 16:11:20 WBPerson2970 Name_change: CGC_name: chc-1
        3 30 Apr 2008 14:28:36 WBPerson2970 Name_change: Other_name: clhc-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: chc
    Allele (82)
    Possibly_affected_by: WBVar02153072
      WBVar00000423
    Strain: WBStrain00037310
      WBStrain00005825
    RNASeq_FPKM (74)
    GO_annotation (34)
    Contained_in_operon: CEOP3858
    Ortholog: WBGene00054928 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00031326 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00157637 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00131044 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00234058 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5173 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g8226 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g17490 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g20495 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g23256 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g20308 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g7289 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g12181 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g535 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g8071 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_07812.g21123 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-chc-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g10212 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00155.g5826 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_22610 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009611 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03024 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03025 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g04741 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g22210 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30209600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g8817 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00211821 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00244635 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00093828 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00104656 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00272192 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00275955 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00275959 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00259227 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287935 Trichuris muris From_analysis: WormBase-Compara
      WBGene00287938 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297849 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000003174 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0000319 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-2299 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050227-12 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-130530-1029 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2092 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2093 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2388633 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:2364 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: chc-1 encodes the C. elegans clathrin heavy chain ortholog; loss of chc-1 activity via RNAi results in defects in receptor-mediated yolk endocytosis and thus, embryonic lethality. Paper_evidence: WBPaper00003831
          Curator_confirmed: WBPerson1843
          Date_last_updated: 21 Mar 2008 00:00:00
      Automated_description: Predicted to enable clathrin light chain binding activity. Involved in several processes, including apical protein localization; determination of adult lifespan; and positive regulation of clathrin-dependent endocytosis. Located in cell periphery; clathrin-coated endocytic vesicle; and mitotic spindle. Expressed in coelomocyte; germ line; hyp7 syncytium; hypodermal cell; and pharyngeal cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Is an ortholog of human CLTC (clathrin heavy chain) and CLTCL1 (clathrin heavy chain like 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080226 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2092)
  Molecular_info: Corresponding_CDS: T20G5.1
    Corresponding_transcript: T20G5.1.1
    Other_sequence (98)
    Associated_feature: WBsf659485
      WBsf659486
      WBsf993933
      WBsf993934
      WBsf1015749
      WBsf225683
  Experimental_info: RNAi_result (68)
    Expr_pattern (13)
    Drives_construct: WBCnstr00000149
      WBCnstr00017705
      WBCnstr00030323
    Construct_product (16)
    Antibody: WBAntibody00000734
      WBAntibody00001390
    Microarray_results (19)
    Expression_cluster (145)
    Interaction (243)
  Map_info: Map: III Position: 2.01234 Error: 0.001699
    Positive: Positive_clone: T20G5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (42)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene