WormBase Tree Display for Gene: WBGene00000047
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WBGene00000047 | SMap | S_parent | Sequence | ZC504 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | acr | ||||||
Allele (53) | |||||||
Strain | WBStrain00031896 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (27) | |||||||
Ortholog (77) | |||||||
Paralog (100) | |||||||
Structured_description | Concise_description | acr-8 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-8 falls into the 'ACR-8' class of nAChR subunits, which includes ACR-12 and ACR-13. | Paper_evidence | WBPaper00005223 | |||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (30) | ||||||
Molecular_info | Corresponding_CDS | ZC504.2 | |||||
Corresponding_CDS_history | ZC504.2:wp54 | ||||||
ZC504.2:wp124 | |||||||
ZC504.2:wp272 | |||||||
Corresponding_transcript | ZC504.2.1 | ||||||
ZC504.2.2 | |||||||
Other_sequence (16) | |||||||
Associated_feature | WBsf718691 | ||||||
WBsf1006700 | |||||||
Experimental_info | RNAi_result | WBRNAi00058977 | Inferred_automatically | RNAi_primary | |||
Expr_pattern | Expr3704 | ||||||
Expr4340 | |||||||
Expr4979 | |||||||
Expr1012528 | |||||||
Expr1030022 | |||||||
Expr1162412 | |||||||
Expr2009197 | |||||||
Expr2027435 | |||||||
Drives_construct (11) | |||||||
Construct_product | WBCnstr00006479 | ||||||
WBCnstr00006480 | |||||||
WBCnstr00011615 | |||||||
WBCnstr00037770 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (122) | |||||||
Interaction | WBInteraction000133959 | ||||||
WBInteraction000136793 | |||||||
WBInteraction000142026 | |||||||
WBInteraction000144320 | |||||||
WBInteraction000209431 | |||||||
WBInteraction000504009 | |||||||
WBInteraction000518504 | |||||||
WBInteraction000543443 | |||||||
Map_info | Map | X | Position | 2.18612 | Error | 0.001806 | |
Positive | Positive_clone | ZC504 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4886 | |||||
4909 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00003425 | ||||||
WBPaper00005223 | |||||||
WBPaper00006324 | |||||||
WBPaper00011839 | |||||||
WBPaper00018912 | |||||||
WBPaper00024530 | |||||||
WBPaper00024783 | |||||||
WBPaper00025218 | |||||||
WBPaper00025762 | |||||||
WBPaper00026249 | |||||||
WBPaper00027611 | |||||||
WBPaper00028231 | |||||||
WBPaper00028761 | |||||||
WBPaper00029012 | |||||||
WBPaper00030363 | |||||||
WBPaper00031105 | |||||||
WBPaper00033737 | |||||||
WBPaper00034730 | |||||||
WBPaper00035364 | |||||||
WBPaper00035548 | |||||||
WBPaper00041227 | |||||||
WBPaper00041959 | |||||||
WBPaper00054426 | |||||||
WBPaper00055090 | |||||||
WBPaper00058964 | |||||||
WBPaper00060283 | |||||||
WBPaper00061589 | |||||||
WBPaper00065144 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |