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WormBase Tree Display for Gene: WBGene00000164

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Name Class

WBGene00000164SMapS_parentSequenceF53H8
IdentityVersion2
NameCGC_nameapm-3Person_evidenceWBPerson360
WBPerson567
Sequence_nameF53H8.1
Molecular_nameF53H8.1
F53H8.1.1
CE35723
Other_nameapt-7Person_evidenceWBPerson625
CELE_F53H8.1Accession_evidenceNDBBX284606
Public_nameapm-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
201 Apr 2005 11:05:24WBPerson2970Name_changeCGC_nameapm-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classapm
Allele (34)
StrainWBStrain00003476
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOPX012
Ortholog (38)
ParalogWBGene00000150Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001082Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006777Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006829Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionapm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.Paper_evidenceWBPaper00004103
WBPaper00004907
WBPaper00005520
WBPaper00013041
WBPaper00025094
Curator_confirmedWBPerson1843
WBPerson324
WBPerson567
Date_last_updated23 Jan 2007 00:00:00
Automated_descriptionInvolved in lipid storage and lysosome organization. Predicted to be located in cytoplasmic vesicle. Predicted to be part of clathrin adaptor complex. Expressed in muscle cell; pharynx; spermatheca; and vulva. Is an ortholog of human AP3M1 (adaptor related protein complex 3 subunit mu 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF53H8.1
Corresponding_CDS_historyF53H8.1:wp108
Corresponding_transcriptF53H8.1.1
Other_sequence (63)
Associated_featureWBsf647808
WBsf662451
WBsf1003904
WBsf1022191
WBsf235299
Experimental_infoRNAi_result (11)
Expr_patternExpr3688
Expr6161
Expr12910
Expr1024542
Expr1030093
Expr1152010
Expr2009362
Expr2027598
Drives_constructWBCnstr00003937
WBCnstr00011600
WBCnstr00037694
Construct_productWBCnstr00022947
WBCnstr00023054
WBCnstr00037694
Microarray_results (22)
Expression_cluster (144)
Interaction (27)
Map_infoMapXPosition-18.8908Error0.004786
PositivePositive_cloneF53H8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4163
4512
Pseudo_map_position
ReferenceWBPaper00004907
WBPaper00005520
WBPaper00025094
WBPaper00025719
WBPaper00026639
WBPaper00028448
WBPaper00028970
WBPaper00029101
WBPaper00030940
WBPaper00031119
WBPaper00032168
WBPaper00036306
WBPaper00038491
WBPaper00049556
WBPaper00053743
WBPaper00055090
WBPaper00062416
WBPaper00062625
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene