WormBase Tree Display for Gene: WBGene00003504

WBGene00003504 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: ZK1098
  Identity: Version: 1
    Name: CGC_name: mut-7 Person_evidence: WBPerson261
      Sequence_name: ZK1098.8
      Molecular_name: ZK1098.8
        ZK1098.8.1
        CE00370
      Other_name: CELE_ZK1098.8 Accession_evidence: NDB BX284603
      Public_name: mut-7
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mut
    Allele (46)
    Strain (5)
    In_cluster: conserved_miRNA_siRNA_cluster
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog (28)
    Paralog: WBGene00014220 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00013256 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00012290 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference. Paper_evidence: WBPaper00003711
            WBPaper00003722
            WBPaper00003956
            WBPaper00004198
            WBPaper00005077
            WBPaper00024699
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 28 Dec 2005 00:00:00
      Automated_description: Predicted to enable 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing. Involved in obsolete negative regulation of transposition, DNA-mediated; olfactory learning; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytosol; mutator focus; and nucleus. Expressed in AWCL; AWCR; and somatic cell. Is an ortholog of human EXD3 (exonuclease 3'-5' domain containing 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1098.8
    Corresponding_transcript: ZK1098.8.1
    Other_sequence: CR03715
      CBC14770_1
      CRC08288_1
    Associated_feature: WBsf667292
      WBsf667293
      WBsf227313
  Experimental_info: RNAi_result (12)
    Expr_pattern (11)
    Drives_construct: WBCnstr00003803
      WBCnstr00014695
      WBCnstr00014696
      WBCnstr00018512
      WBCnstr00036084
    Construct_product: WBCnstr00014695
      WBCnstr00014696
      WBCnstr00018512
      WBCnstr00036084
    Antibody: WBAntibody00000828
    Microarray_results (20)
    Expression_cluster (133)
    Interaction (31)
    WBProcess: WBbiopr:00000057
  Map_info: Map: III Position: 0.579676 Error: 0.00167
    Positive: Positive_clone: ZK1098 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4504
        4993
    Pseudo_map_position
  Reference: WBPaper00003711
    WBPaper00003722
    WBPaper00003763
    WBPaper00003918
    WBPaper00003956
    WBPaper00003963
    WBPaper00003964
    WBPaper00004139
    WBPaper00004173
    WBPaper00004198
    WBPaper00004325
    WBPaper00004507
    WBPaper00004549
    WBPaper00004563
    WBPaper00004605
    WBPaper00004757
    WBPaper00005077
    WBPaper00005193
    WBPaper00005284
    WBPaper00005368
    WBPaper00005423
    WBPaper00005667
    WBPaper00006028
    WBPaper00006203
    WBPaper00006267
    WBPaper00006297
    WBPaper00010177
    WBPaper00010533
    WBPaper00011220
    WBPaper00011269
    WBPaper00011345
    WBPaper00011424
    WBPaper00011573
    WBPaper00011607
    WBPaper00011629
    WBPaper00011638
    WBPaper00011706
    WBPaper00011808
    WBPaper00011863
    WBPaper00011944
    WBPaper00013439
    WBPaper00015214
    WBPaper00015327
    WBPaper00015481
    WBPaper00015490
    WBPaper00015501
    WBPaper00015546
    WBPaper00015668
    WBPaper00015688
    WBPaper00016769
    WBPaper00016893
    WBPaper00017538
    WBPaper00017730
    WBPaper00017752
    WBPaper00017893
    WBPaper00017894
    WBPaper00017907
    WBPaper00018026
    WBPaper00018185
    WBPaper00018225
    WBPaper00018227
    WBPaper00018228
    WBPaper00018497
    WBPaper00018874
    WBPaper00018875
    WBPaper00019022
    WBPaper00022241
    WBPaper00022930
    WBPaper00022952
    WBPaper00023721
    WBPaper00023857
    WBPaper00024202
    WBPaper00024258
    WBPaper00024434
    WBPaper00024516
    WBPaper00024699
    WBPaper00024726
    WBPaper00025510
    WBPaper00026593
    WBPaper00026665
    WBPaper00027111
    WBPaper00027312
    WBPaper00028464
    WBPaper00028740
    WBPaper00029328
    WBPaper00029370
    WBPaper00030183
    WBPaper00030543
    WBPaper00031484
    WBPaper00031961
    WBPaper00031962
    WBPaper00032049
    WBPaper00032178
    WBPaper00032860
    WBPaper00034578
    WBPaper00034840
    WBPaper00035245
    WBPaper00038050
    WBPaper00038088
    WBPaper00038491
    WBPaper00038505
    WBPaper00038888
    WBPaper00038893
    WBPaper00038973
    WBPaper00039118
    WBPaper00041208
    WBPaper00042637
    WBPaper00042831
    WBPaper00042834
    WBPaper00043989
    WBPaper00044120
    WBPaper00045091
    WBPaper00045604
    WBPaper00046416
    WBPaper00047219
    WBPaper00047223
    WBPaper00047833
    WBPaper00050362
    WBPaper00052346
    WBPaper00052477
    WBPaper00055090
    WBPaper00058266
    WBPaper00058354
    WBPaper00059651
    WBPaper00060750
    WBPaper00061101
    WBPaper00062308
    WBPaper00063882
    WBPaper00065106
  Remark: Sequence connection from [Ketting RF]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene