WormBase Tree Display for Gene: HGNC:3014
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HGNC:3014 | Identity (4) | |||||
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Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00000963 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
Inparanoid | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
WBGene00006769 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
Panther | ||||||
WBGene00000964 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
Inparanoid | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] | Inferred_automatically | AGR_import |