WormBase Tree Display for Gene: HGNC:7804
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HGNC:7804 | Identity | Name | CGC_name | Nfya | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (15) | ||||||
Public_name | Nfya | |||||
DB_info | Database | HGNC | id | 7804 | ||
AGR | cURI | HGNC:7804 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000001167 | ||||
UniProt | UniProt_AC | P23511 | ||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00011614 | Caenorhabditis elegans | From_analysis | OrthoFinder | ||
OrthoInspector | ||||||
Panther | ||||||
WBGene00043056 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
Structured_description | Automated_description | The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |