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WormBase Tree Display for Gene: HGNC:7804

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Name Class

HGNC:7804IdentityNameCGC_nameNfyaInferred_automaticallyAGR_import
Other_name (15)
Public_nameNfya
DB_infoDatabaseHGNCid7804
AGRcURIHGNC:7804
EnsEMBLENSEMBL_geneIDENSG00000001167
UniProtUniProt_ACP23511
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00011614Caenorhabditis elegansFrom_analysisOrthoFinder
OrthoInspector
Panther
WBGene00043056Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
OrthoInspector
Panther
Structured_descriptionAutomated_descriptionThe protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import