WormBase Tree Display for Gene: HGNC:9083
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| HGNC:9083 | Identity | Name | CGC_name | Plod3 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1346467 | |||||
| LH3 | ||||||
| lysine hydroxylase 3 | ||||||
| lysyl hydroxlase 3 | ||||||
| lysyl hydroxylase 3 | ||||||
| multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 | ||||||
| procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | ||||||
| Public_name | Plod3 | |||||
| DB_info | Database | HGNC | id | 9083 | ||
| AGR | cURI | HGNC:9083 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000106397 | ||||
| UniProt | UniProt_AC | O60568 | ||||
| DO | id | DOID:684 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00002497 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |
