WormBase Tree Display for Gene: RGD:3959
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| RGD:3959 | Identity | Name | CGC_name | Vdr | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Vdr | |||||
| DB_info | Database | RGD | id | 3959 | ||
| AGR | cURI | RGD:3959 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000054420 | ||||
| UniProt | UniProt_AC | P13053 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00003607 | Caenorhabditis elegans | From_analysis | Inparanoid | ||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00000908 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| OrthoInspector | ||||||
| Panther | ||||||
| WBGene00003638 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| OrthoInspector | ||||||
| Panther | ||||||
| Structured_description | Automated_description | Enables calcitriol binding activity; nuclear receptor activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to amyloid-beta; negative regulation of bone trabecula formation; and positive regulation of parathyroid hormone secretion. Located in T-tubule; nuclear lumen; and perinuclear region of cytoplasm. Part of euchromatin and heterochromatin. Colocalizes with caveola. Used to study vitamin D-dependent rickets type 2A. Biomarker of retinal degeneration and secondary hyperparathyroidism. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); lipid storage disease (multiple); lung disease (multiple); and melanoma (multiple). Orthologous to human VDR (vitamin D receptor); PARTICIPATES IN altered p53 signaling pathway; tuberculosis pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 17beta-estradiol. | Inferred_automatically | AGR_import |
