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WormBase Tree Display for Gene: WBGene00000020

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Name Class

WBGene00000020EvidencePerson_evidenceWBPerson583
WBPerson36
SMapS_parentSequenceCHROMOSOME_I
IdentityVersion2
NameCGC_nameabt-2Person_evidenceWBPerson36
Sequence_nameF12B6.1
Molecular_nameF12B6.1a
F12B6.1a.1
CE40156
F12B6.1b
CE49736
F12B6.1b.1
Other_nameY39G10AL.bCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_F12B6.1Accession_evidenceNDBBX284601
Public_nameabt-2
DB_infoDatabaseAceViewgene1C828
WormQTLgeneWBGene00000020
WormFluxgeneWBGene00000020
NDBlocus_tagCELE_F12B6.1
PanthergeneCAEEL|WormBase=WBGene00000020|UniProtKB=Q1RS86
familyPTHR19229
NCBIgene171782
RefSeqproteinNM_058548.7
NM_001381367.1
TrEMBLUniProtAccQ1RS86
X5LXB2
UniProt_GCRPUniProtAccQ1RS86
OMIMgene600046
601691
605414
607800
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:19WBPerson1971EventImportedInitial conversion from geneace
206 Apr 2006 16:52:19WBPerson2970EventAcquires_mergeWBGene00021459
Acquires_mergeWBGene00021459
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classabt
Allele (307)
StrainWBStrain00031555
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (73)
ParalogWBGene00000019Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000421Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000022Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000023Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionabt-2 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-2 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes.Paper_evidenceWBPaper00006421
Curator_confirmedWBPerson1843
Date_last_updated24 Jul 2012 00:00:00
Automated_descriptionPredicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 9; autosomal recessive congenital ichthyosis (multiple); hypolipoproteinemia (multiple); and retinal degeneration (multiple). Is an ortholog of human ABCA12 (ATP binding cassette subfamily A member 12).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (22)
Molecular_infoCorresponding_CDSF12B6.1a
F12B6.1b
Corresponding_CDS_historyF12B6.1:wp156
Corresponding_transcriptF12B6.1a.1
F12B6.1b.1
Other_sequence (41)
Associated_feature (12)
Experimental_infoRNAi_resultWBRNAi00044430Inferred_automaticallyRNAi_primary
WBRNAi00056260Inferred_automaticallyRNAi_primary
WBRNAi00003366Inferred_automaticallyRNAi_primary
Expr_patternExpr3314
Expr3315
Expr1018096
Expr1030007
Expr1148376
Expr2009095
Expr2027331
Drives_constructWBCnstr00011310
WBCnstr00011311
WBCnstr00037792
Construct_productWBCnstr00037792
Microarray_results (25)
Expression_cluster (140)
Interaction (20)
Map_infoMapIPosition-10.4952Error0.191835
PositivePositive_cloneF12B6Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4198
5628
5674
Pseudo_map_position
ReferenceWBPaper00006421
WBPaper00027644
WBPaper00031484
WBPaper00038491
WBPaper00052700
WBPaper00055090
WBPaper00058442
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene