WormBase Tree Display for Gene: WBGene00000022
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WBGene00000022 | Evidence | Person_evidence | WBPerson583 | ||||||
---|---|---|---|---|---|---|---|---|---|
WBPerson36 | |||||||||
SMap | S_parent | Sequence | CHROMOSOME_V | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | abt-4 | Person_evidence | WBPerson36 | |||||
Sequence_name | Y39D8C.1 | ||||||||
Molecular_name | Y39D8C.1 | ||||||||
Y39D8C.1.1 | |||||||||
CE20234 | |||||||||
Other_name | CELE_Y39D8C.1 | Accession_evidence | NDB | BX284605 | |||||
Public_name | abt-4 | ||||||||
DB_info | Database | AceView | gene | 5A802 | |||||
WormQTL | gene | WBGene00000022 | |||||||
WormFlux | gene | WBGene00000022 | |||||||
NDB | locus_tag | CELE_Y39D8C.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000022|UniProtKB=Q9TXV8 | |||||||
family | PTHR19229 | ||||||||
NCBI | gene | 178559 | |||||||
RefSeq | protein | NM_070774.5 | |||||||
TrEMBL | UniProtAcc | Q9TXV8 | |||||||
UniProt_GCRP | UniProtAcc | Q9TXV8 | |||||||
OMIM | gene | 601615 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | abt | ||||||||
Allele (140) | |||||||||
Strain | WBStrain00031530 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (64) | |||||||||
Paralog | WBGene00000019 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00000020 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00000421 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00000023 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | abt-4 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-4 activity via RNAi results in no obvious defects, the precise role of abt-4 in C. elegans development and/or behavior is not yet known; abt-4 promoter-gfp fusion proteins are widely expressed in larvae and adults, with expression seen in the pharynx, the pharyngeal-intestinal valve, the intestine, renal gland cells, hypodermis, various neurons, and unidentified cells in the head and tail. | Paper_evidence | WBPaper00006421 | |||||
WBPaper00006525 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 06 Mar 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Expressed in head and tail. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Is an ortholog of human ABCA3 (ATP binding cassette subfamily A member 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:12120 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:33) | ||||
Molecular_info | Corresponding_CDS | Y39D8C.1 | |||||||
Corresponding_transcript | Y39D8C.1.1 | ||||||||
Other_sequence (31) | |||||||||
Associated_feature | WBsf999132 | ||||||||
WBsf999133 | |||||||||
WBsf1019057 | |||||||||
WBsf233262 | |||||||||
Experimental_info | RNAi_result | WBRNAi00020400 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056229 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00014251 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00117472 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00056230 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram1445 | ||||||||
Expr3320 | |||||||||
Expr6954 | |||||||||
Expr6955 | |||||||||
Expr1028601 | |||||||||
Expr1030008 | |||||||||
Expr1159719 | |||||||||
Expr2009096 | |||||||||
Expr2027332 | |||||||||
Drives_construct | WBCnstr00004250 | ||||||||
WBCnstr00011316 | |||||||||
WBCnstr00037791 | |||||||||
Construct_product | WBCnstr00037791 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (199) | |||||||||
Interaction (26) | |||||||||
Map_info | Map | V | Position | -20.0035 | |||||
Positive | Positive_clone | Y39D8C | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4135 | |||||||
5417 | |||||||||
5578 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00006421 | ||||||||
WBPaper00027644 | |||||||||
WBPaper00031006 | |||||||||
WBPaper00031484 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056449 | |||||||||
WBPaper00060859 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |