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WormBase Tree Display for Gene: WBGene00000022

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Name Class

WBGene00000022EvidencePerson_evidenceWBPerson583
WBPerson36
SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_nameabt-4Person_evidenceWBPerson36
Sequence_nameY39D8C.1
Molecular_nameY39D8C.1
Y39D8C.1.1
CE20234
Other_nameCELE_Y39D8C.1Accession_evidenceNDBBX284605
Public_nameabt-4
DB_infoDatabaseAceViewgene5A802
WormQTLgeneWBGene00000022
WormFluxgeneWBGene00000022
NDBlocus_tagCELE_Y39D8C.1
PanthergeneCAEEL|WormBase=WBGene00000022|UniProtKB=Q9TXV8
familyPTHR19229
NCBIgene178559
RefSeqproteinNM_070774.5
TrEMBLUniProtAccQ9TXV8
UniProt_GCRPUniProtAccQ9TXV8
OMIMgene601615
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:19WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classabt
Allele (140)
StrainWBStrain00031530
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (64)
ParalogWBGene00000019Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000020Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000421Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000023Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionabt-4 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-4 activity via RNAi results in no obvious defects, the precise role of abt-4 in C. elegans development and/or behavior is not yet known; abt-4 promoter-gfp fusion proteins are widely expressed in larvae and adults, with expression seen in the pharynx, the pharyngeal-intestinal valve, the intestine, renal gland cells, hypodermis, various neurons, and unidentified cells in the head and tail.Paper_evidenceWBPaper00006421
WBPaper00006525
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated06 Mar 2006 00:00:00
Automated_descriptionPredicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Expressed in head and tail. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Is an ortholog of human ABCA3 (ATP binding cassette subfamily A member 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12120Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:33)
Molecular_infoCorresponding_CDSY39D8C.1
Corresponding_transcriptY39D8C.1.1
Other_sequence (31)
Associated_featureWBsf999132
WBsf999133
WBsf1019057
WBsf233262
Experimental_infoRNAi_resultWBRNAi00020400Inferred_automaticallyRNAi_primary
WBRNAi00056229Inferred_automaticallyRNAi_primary
WBRNAi00014251Inferred_automaticallyRNAi_primary
WBRNAi00117472Inferred_automaticallyRNAi_primary
WBRNAi00056230Inferred_automaticallyRNAi_primary
Expr_patternChronogram1445
Expr3320
Expr6954
Expr6955
Expr1028601
Expr1030008
Expr1159719
Expr2009096
Expr2027332
Drives_constructWBCnstr00004250
WBCnstr00011316
WBCnstr00037791
Construct_productWBCnstr00037791
Microarray_results (19)
Expression_cluster (199)
Interaction (26)
Map_infoMapVPosition-20.0035
PositivePositive_cloneY39D8CInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4135
5417
5578
Pseudo_map_position
ReferenceWBPaper00006421
WBPaper00027644
WBPaper00031006
WBPaper00031484
WBPaper00038491
WBPaper00055090
WBPaper00056449
WBPaper00060859
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene