WormBase Tree Display for Gene: WBGene00000071
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| WBGene00000071 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | acy-4 | Person_evidence | WBPerson1139 | |||||
| Sequence_name | T01C2.1 | ||||||||
| Molecular_name | T01C2.1 | ||||||||
| T01C2.1.1 | |||||||||
| CE42417 | |||||||||
| Other_name | CELE_T01C2.1 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | acy-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acy | ||||||||
| Allele (94) | |||||||||
| Strain | WBStrain00036520 | ||||||||
| WBStrain00005680 | |||||||||
| WBStrain00005681 | |||||||||
| WBStrain00005684 | |||||||||
| WBStrain00005685 | |||||||||
| WBStrain00005722 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (58) | |||||||||
| Paralog (36) | |||||||||
| Structured_description | Concise_description | acy-4 encodes an adenylate cyclase most similar to vertebrate type V and type VI adenylate cyclases; by homology, ACY-4 is a predicted plasma membrane protein that catalyzes the conversion of ATP to cyclic AMP, a key second messenger in intracellular signaling. | Paper_evidence | WBPaper00003207 | |||||
| WBPaper00004651 | |||||||||
| WBPaper00018521 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 23 Jul 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable adenylate cyclase activity. Involved in oocyte growth. Acts upstream of or within with a positive effect on oocyte maturation. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44 and lethal congenital contracture syndrome. Is an ortholog of human ADCY6 (adenylate cyclase 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060558 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:237) | ||||
| EFO:MONDO:0031115 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:236) | ||||||
| DOID:0110501 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:232) | ||||||
| Molecular_info | Corresponding_CDS | T01C2.1 | |||||||
| Corresponding_CDS_history | T01C2.1:wp104 | ||||||||
| T01C2.1:wp131 | |||||||||
| T01C2.1:wp188 | |||||||||
| Corresponding_transcript | T01C2.1.1 | ||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf717225 | ||||||||
| WBsf1000046 | |||||||||
| WBsf1000047 | |||||||||
| WBsf1000048 | |||||||||
| WBsf1019664 | |||||||||
| WBsf1019665 | |||||||||
| WBsf1019666 | |||||||||
| WBsf233706 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00052091 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00050870 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001886 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00050869 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1017064 | ||||||||
| Expr1030031 | |||||||||
| Expr1155722 | |||||||||
| Expr2009230 | |||||||||
| Expr2027467 | |||||||||
| Drives_construct | WBCnstr00037753 | ||||||||
| Construct_product | WBCnstr00006740 | ||||||||
| WBCnstr00037753 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (116) | |||||||||
| Interaction (98) | |||||||||
| WBProcess | WBbiopr:00000120 | ||||||||
| Map_info | Map | V | Position | -1.33183 | Error | 0.00393 | |||
| Positive | Positive_clone | T01C2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Picture | WBPicture0000013094 | ||||||||
| Remark | Sequence connection from [Plasterk RHA] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
