WormBase Tree Display for Gene: WBGene00000271
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| WBGene00000271 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F45E12 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | brf-1 | |||||||
| Sequence_name | F45E12.2 | ||||||||
| Molecular_name | F45E12.2a | ||||||||
| F45E12.2a.1 | |||||||||
| CE51435 | |||||||||
| F45E12.2b | |||||||||
| CE51360 | |||||||||
| F45E12.2b.1 | |||||||||
| Other_name | CELE_F45E12.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | brf-1 | ||||||||
| DB_info | Database | AceView | gene | 2H597 | |||||
| WormQTL | gene | WBGene00000271 | |||||||
| WormFlux | gene | WBGene00000271 | |||||||
| NDB | locus_tag | CELE_F45E12.2 | |||||||
| Panther | gene | CAEEL|Gene_ORFName=CELE_F45E12.2|UniProtKB=A0A131MCT5 | |||||||
| family | PTHR11618 | ||||||||
| NCBI | gene | 174199 | |||||||
| RefSeq | protein | NM_001322740.4 | |||||||
| NM_001322739.4 | |||||||||
| TrEMBL | UniProtAcc | A0A131MCT5 | |||||||
| A0A131MBG0 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A131MCT5 | |||||||
| OMIM | gene | 604902 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | brf | ||||||||
| Allele (33) | |||||||||
| Strain | WBStrain00035490 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP2296 | ||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00006648 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | brf-1 encodes an ortholog of mammalian B-RELATED FACTOR (also known as BRF, TDS4, PCF4, or hTFIIIB90); BRF is thought to act as a molecular bridge between TATA-binding protein (TBP) associated factors that functions in TFIIIB (RNA polymerase III associated transcription factors). | Paper_evidence | WBPaper00003396 | |||||
| WBPaper00017723 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| WBPerson480 | |||||||||
| Date_last_updated | 24 Jan 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase III general transcription initiation factor activity and RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription initiation and transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Human ortholog(s) of this gene implicated in cerebellofaciodental syndrome. Is an ortholog of human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080898 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11551) | ||||
| Molecular_info | Corresponding_CDS | F45E12.2a | |||||||
| F45E12.2b | |||||||||
| Corresponding_CDS_history | F45E12.2:wp252 | ||||||||
| Corresponding_transcript | F45E12.2a.1 | ||||||||
| F45E12.2b.1 | |||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf657814 | ||||||||
| WBsf988396 | |||||||||
| WBsf221584 | |||||||||
| WBsf221585 | |||||||||
| Transcription_factor | WBTranscriptionFactor000149 | ||||||||
| WBTranscriptionFactor000248 | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr1025497 | ||||||||
| Expr1030175 | |||||||||
| Expr1151242 | |||||||||
| Expr2009656 | |||||||||
| Expr2027895 | |||||||||
| Drives_construct | WBCnstr00037614 | ||||||||
| Construct_product | WBCnstr00037614 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (93) | |||||||||
| Interaction (90) | |||||||||
| Map_info | Map | II | Position | 0.501147 | Error | 0.000153 | |||
| Positive | Positive_clone | F45E12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4171 | |||||||
| 4615 | |||||||||
| 5564 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003396 | ||||||||
| WBPaper00027309 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Sequence connection from [Larminie CG, White RJ] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
