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WormBase Tree Display for Gene: WBGene00000410

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Name Class

WBGene00000410SMapS_parentSequenceCHROMOSOME_I
IdentityVersion1
NameCGC_namecdk-9Person_evidenceWBPerson346
Sequence_nameH25P06.2
Molecular_nameH25P06.2a
H25P06.2a.1
CE37838
H25P06.2b
CE37839
H25P06.2b.1
Other_nameCELE_H25P06.2Accession_evidenceNDBBX284601
Public_namecdk-9
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcdk
Allele (164)
StrainWBStrain00024047
WBStrain00024060
WBStrain00024061
WBStrain00024067
WBStrain00024066
RNASeq_FPKM (74)
GO_annotation (26)
Ortholog (43)
Paralog (17)
Structured_descriptionConcise_descriptioncdk-9 encodes an ortholog of the metazoan transcription elongation factor kinase CDK-9; it is required for general expression of early embryonic genes, and thought (in conjunction with partners such as cyclin T) to form a transcription factor (P-TEFb) that which prevents transcription from stalling in vitro.Paper_evidenceWBPaper00004192
WBPaper00005411
WBPaper00012800
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in embryo development; germ cell development; and nematode larval development. Part of euchromatin. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in congestive heart failure. Is an ortholog of human CDK9 (cyclin dependent kinase 9).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:6000Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1780)
Molecular_infoCorresponding_CDSH25P06.2a
H25P06.2b
Corresponding_CDS_historyH25P06.2a:wp136
H25P06.2b:wp136
Corresponding_transcriptH25P06.2a.1
H25P06.2b.1
Other_sequenceCR01437
CRC07475_1
CRC07674_1
CR11356
Associated_featureWBsf985267
WBsf985268
WBsf218528
Transcription_factorWBTranscriptionFactor000152
Experimental_infoRNAi_result (24)
Expr_patternExpr11659
Expr1014827
Expr1030227
Expr1153215
Expr2009815
Expr2028056
Construct_productWBCnstr00019154
WBCnstr00019155
WBCnstr00019280
WBCnstr00019281
WBCnstr00019282
AntibodyWBAntibody00000536
Microarray_results (32)
Expression_cluster (79)
Interaction (60)
Map_infoMapIPosition7.94628Error0.001706
PositivePositive_cloneH25P06Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (20)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene