WormBase Tree Display for Gene: WBGene00000566
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| WBGene00000566 | Evidence | Accession_evidence | EMBL | AJ132700 | |||||
|---|---|---|---|---|---|---|---|---|---|
| AJ132701 | |||||||||
| SMap | S_parent | Sequence | Y39A1A | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | cnt-2 | |||||||
| Sequence_name | Y39A1A.15 | ||||||||
| Molecular_name (21) | |||||||||
| Other_name | cnt-2a | Accession_evidence | EMBL | AJ132700 | |||||
| cnt-2b | Accession_evidence | EMBL | AJ132701 | ||||||
| CELE_Y39A1A.15 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | cnt-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cnt | ||||||||
| Allele (394) | |||||||||
| Strain | WBStrain00032196 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP3692 | ||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00008805 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00044808 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | ||||||
| WBGene00000565 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010500 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012359 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00017217 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00017760 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | cnt-2 encodes an Arf GTPase-activating protein (GAP) of the AGAP family; cnt-2 is required for asymmetric cell divisions; genetic analyses suggest that cnt-2 influences asymmetric cell divisions through regulation of receptor-mediated endocytosis and regulation of actomyosin dynamics at the cell cortex. | Paper_evidence | WBPaper00038432 | |||||
| WBPaper00041831 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 29 Jan 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activator activity and GTPase activity. Involved in asymmetric neuroblast division; cell fate determination involved in pattern specification; and regulation of receptor-mediated endocytosis. Expressed in tail. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma and prostate cancer. Is an ortholog of human AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16921) | ||||
| DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16921) | ||||||
| Molecular_info | Corresponding_CDS | Y39A1A.15a | |||||||
| Y39A1A.15b | |||||||||
| Y39A1A.15c | |||||||||
| Y39A1A.15e | |||||||||
| Y39A1A.15f | |||||||||
| Y39A1A.15g | |||||||||
| Corresponding_CDS_history | Y39A1A.15a:wp52 | ||||||||
| Y39A1A.15d:wp275 | |||||||||
| Corresponding_transcript | Y39A1A.15a.1 | ||||||||
| Y39A1A.15b.1 | |||||||||
| Y39A1A.15b.2 | |||||||||
| Y39A1A.15c.1 | |||||||||
| Y39A1A.15e.1 | |||||||||
| Y39A1A.15e.2 | |||||||||
| Y39A1A.15e.3 | |||||||||
| Y39A1A.15f.1 | |||||||||
| Y39A1A.15g.1 | |||||||||
| Other_sequence (39) | |||||||||
| Associated_feature (37) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00056098 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00098331 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062426 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036881 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062427 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061546 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006157 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098436 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061651 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020341 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram853 | ||||||||
| Chronogram1619 | |||||||||
| Expr6940 | |||||||||
| Expr6941 | |||||||||
| Expr1028905 | |||||||||
| Expr1030342 | |||||||||
| Expr1159619 | |||||||||
| Expr2010285 | |||||||||
| Expr2028527 | |||||||||
| Drives_construct | WBCnstr00002326 | ||||||||
| Construct_product (17) | |||||||||
| Microarray_results (44) | |||||||||
| Expression_cluster (140) | |||||||||
| Interaction (45) | |||||||||
| Map_info | Map | III | Position | 4.39408 | Error | 0.040675 | |||
| Positive | Positive_clone | Y39A1A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
