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WormBase Tree Display for Gene: WBGene00000763

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Name Class

WBGene00000763EvidencePaper_evidenceWBPaper00005078
WBPaper00013270
SMapS_parentSequenceY57G11C
IdentityVersion2
NameCGC_namecoq-3Person_evidenceWBPerson247
Sequence_nameY57G11C.11
Molecular_nameY57G11C.11a
Y57G11C.11a.1
CE14946
Y57G11C.11b
Y57G11C.11c
Other_nameCELE_Y57G11C.11Accession_evidenceNDBBX284604
Public_namecoq-3
DB_infoDatabaseWormQTLgeneWBGene00000763
WormFluxgeneWBGene00000763
NDBlocus_tagCELE_Y57G11C.11
PanthergeneCAEEL|WormBase=WBGene00000763|UniProtKB=O18235
familyPTHR43464
NCBIgene178403
RefSeqproteinNR_131652.1
NM_001047580.5
NR_131651.1
TREEFAMTREEFAM_IDTF314553
TrEMBLUniProtAccO18235
UniProt_GCRPUniProtAccO18235
RNAcentralURSidURS0000763C7D
URS000076C18D
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
212 Jul 2006 17:04:09WBPerson4025EventChanged_classPseudogeneCDS
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcoq
Allele (57)
StrainWBStrain00001500
WBStrain00026673
WBStrain00035769
RNASeq_FPKM (74)
GO_annotation (30)
Contained_in_operonCEOP4580
Ortholog (38)
ParalogWBGene00015999Caenorhabditis elegansFrom_analysisPanther
WBGene00016023Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptioncoq-3 encodes a putative 3,4-dihydroxy-5-hexaprenylbenzoatemethyltransferase, orthologous to S. cerevisiae COQ3; by orthology, COQ-3is predicted to be in a complex with COQ-4 (and perhaps COQ-6), and to berequired for two different steps of ubiquinone synthesis; COQ-3 isrequired for viability, ubiquinone (coenzyme Q9) biosynthesis and fornormally short lifespan; coq-3 null mutations are lethal; coq-3(RNAi)animals have reduced levels of coenzyme Q9 and superoxide, and haveabnormally long lifespans.Paper_evidenceWBPaper00005078
WBPaper00005863
WBPaper00012777
WBPaper00013532
WBPaper00028311
Curator_confirmedWBPerson567
Date_last_updated11 Aug 2006 00:00:00
Automated_descriptionPredicted to enable hexaprenyldihydroxybenzoate methyltransferase activity. Involved in nematode larval development and ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Is an ortholog of human COQ3 (coenzyme Q3, methyltransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY57G11C.11a
Corresponding_CDS_historyY57G11C.11b:wp243
Corresponding_transcriptY57G11C.11b
Y57G11C.11c
Y57G11C.11a.1
Other_sequence (32)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00022972Inferred_automaticallyRNAi_primary
WBRNAi00057682Inferred_automaticallyRNAi_primary
WBRNAi00021135Inferred_automaticallyRNAi_primary
WBRNAi00103621Inferred_automaticallyRNAi_primary
WBRNAi00037592Inferred_automaticallyRNAi_primary
Expr_patternChronogram1084
Expr7076
Expr1024457
Expr1161091
Expr2010463
Expr2028703
Drives_constructWBCnstr00002357
AntibodyWBAntibody00002368
Microarray_results (31)
Expression_cluster (103)
Interaction (54)
Map_infoMapIVPosition12.503Error0.01219
PositivePositive_cloneY57G11CInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4235
4290
Pseudo_map_position
Reference (18)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene