WormBase Tree Display for Gene: WBGene00000820

WBGene00000820 SMap: S_parent: Sequence: Y73B6BL
  Identity: Version: 1
    Name: CGC_name: csp-2 Person_evidence: WBPerson576
      Sequence_name: Y73B6BL.7
      Molecular_name: Y73B6BL.7a
        Y73B6BL.7a.1
        CE28270
        Y73B6BL.7b
        CE51898
        Y73B6BL.7c
        CE51881
        Y73B6BL.7b.1
        Y73B6BL.7c.1
      Other_name: CELE_Y73B6BL.7 Accession_evidence: NDB BX284604
      Public_name: csp-2
    DB_info: Database: AceView gene 4H79
        WormQTL gene WBGene00000820
        WormFlux gene WBGene00000820
        NDB locus_tag CELE_Y73B6BL.7
        Panther gene CAEEL|WormBase=WBGene00000820|UniProtKB=Q9TZP5
          family PTHR10454
        NCBI gene 177391
        RefSeq protein NM_001383103.2
            NM_001380264.1
            NM_001380265.1
        SwissProt UniProtAcc Q9TZP5
        UniProt_GCRP UniProtAcc Q9TZP5
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: csp
    Allele (95)
    Strain: WBStrain00032182
      WBStrain00027533
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (12)
    Paralog: WBGene00000417 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000819 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000821 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: The csp-2 gene encodes a caspase homolog that may be involved in apoptosis. Paper_evidence: WBPaper00004589
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables caspase binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and zymogen binding activity. Involved in positive regulation of brood size; positive regulation of fertilization; and regulation of apoptotic process. Part of protease inhibitor complex. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); chronic myeloid leukemia; and ductal carcinoma in situ. Is an ortholog of human CASP6 (caspase 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1507)
      DOID:8552 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1507)
      DOID:0060074 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1507)
      DOID:3908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1507)
      DOID:11132 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1507)
      DOID:4001 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1507)
  Molecular_info: Corresponding_CDS: Y73B6BL.7a
      Y73B6BL.7b
      Y73B6BL.7c
    Corresponding_CDS_history: Y73B6BL.7:wp240
      Y73B6BL.7c:wp261
    Corresponding_transcript: Y73B6BL.7a.1
      Y73B6BL.7b.1
      Y73B6BL.7c.1
    Associated_feature: WBsf996723
      WBsf1017505
      WBsf1017506
  Experimental_info: RNAi_result: WBRNAi00107038 Inferred_automatically: RNAi_primary
      WBRNAi00004667 Inferred_automatically: RNAi_primary
      WBRNAi00056851 Inferred_automatically: RNAi_primary
      WBRNAi00058345 Inferred_automatically: RNAi_primary
      WBRNAi00113702 Inferred_automatically: RNAi_primary
      WBRNAi00056846 Inferred_automatically: RNAi_primary
      WBRNAi00107026 Inferred_automatically: RNAi_primary
      WBRNAi00113706 Inferred_automatically: RNAi_primary
      WBRNAi00106826 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8996
      Expr10791
      Expr1013485
      Expr1030510
      Expr1161762
      Expr2010558
      Expr2028798
    Drives_construct: WBCnstr00005664
    Construct_product: WBCnstr00005664
      WBCnstr00005665
    Microarray_results (17)
    Expression_cluster (136)
    Interaction: WBInteraction000133983
      WBInteraction000133985
      WBInteraction000288548
      WBInteraction000540792
      WBInteraction000541997
      WBInteraction000542408
      WBInteraction000542416
  Map_info: Map: IV Position: 3.1478 Error: 0.002982
    Positive: Positive_clone: Y73B6BL Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4839
        4852
        4803
        4819
    Pseudo_map_position
  Reference (24)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene