WormBase Tree Display for Gene: WBGene00000895
expand all nodes | collapse all nodes | view schema
WBGene00000895 | SMap | S_parent | Sequence | B0412 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | dac-1 | Person_evidence | WBPerson473 | |||||
Sequence_name | B0412.1 | ||||||||
Molecular_name | B0412.1a | ||||||||
B0412.1a.1 | |||||||||
CE26848 | |||||||||
B0412.1b | |||||||||
CE33550 | |||||||||
B0412.1b.1 | |||||||||
Other_name | ski-1 | Person_evidence | WBPerson473 | ||||||
CELE_B0412.1 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | dac-1 | ||||||||
DB_info | Database | AceView | gene | 3B439 | |||||
WormQTL | gene | WBGene00000895 | |||||||
WormFlux | gene | WBGene00000895 | |||||||
NDB | locus_tag | CELE_B0412.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000895|UniProtKB=H2KY91 | |||||||
family | PTHR12577 | ||||||||
NCBI | gene | 175238 | |||||||
RefSeq | protein | NM_001025959.5 | |||||||
NM_001025958.4 | |||||||||
SwissProt | UniProtAcc | H2KY91 | |||||||
TREEFAM | TREEFAM_ID | TF316697 | |||||||
UniProt_GCRP | UniProtAcc | H2KY91 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | dac | ||||||||
Allele (159) | |||||||||
Strain | WBStrain00001324 | ||||||||
WBStrain00001325 | |||||||||
WBStrain00035649 | |||||||||
WBStrain00035733 | |||||||||
WBStrain00035736 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00021457 | ||||||||
00021458 | |||||||||
00021459 | |||||||||
00021460 | |||||||||
00021461 | |||||||||
00021462 | |||||||||
00021463 | |||||||||
00021464 | |||||||||
00021465 | |||||||||
Ortholog (36) | |||||||||
Structured_description | Concise_description | dac-1 encodes the C. elegans ortholog of Dachshund, a transcriptional regulator first described in Drosophila that is a member of the SKI/SNO/DAC family of proteins; dac-1 is expressed at higher levels in the AFD thermosensory neurons as compared to the AWB olfactory neurons and likely plays a role in thermosensory behavior as on thermal gradients dac-1 mutants fail to suppress cryophilic drive but continue to track isotherms at the cultivation temperature; a DAC-1::GFP fusion protein is nuclear and expressed strongly in the AFD thermosensory neurons, but weakly in the AWC, ASE, and ASK chemosensory neurons; expression is also seen in alae and additional, unidentified tail cells; dac-1 expression in AFD is positively regulated by the TTX-1 OTX-like homeodomain protein. | Paper_evidence | WBPaper00024671 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 21 May 2007 00:00:00 | ||||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in thermotaxis. Located in nucleus. Expressed in amphid neurons; cuticular ala; and tail. Is an ortholog of human DACH1 (dachshund family transcription factor 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | B0412.1a | |||||||
B0412.1b | |||||||||
Corresponding_CDS_history | B0412.1b:wp120 | ||||||||
B0412.1b:wp123 | |||||||||
Corresponding_transcript | B0412.1a.1 | ||||||||
B0412.1b.1 | |||||||||
Other_sequence (4) | |||||||||
Associated_feature | WBsf658584 | ||||||||
WBsf978943 | |||||||||
WBsf224400 | |||||||||
Transcription_factor | WBTranscriptionFactor000635 | ||||||||
Experimental_info (8) | |||||||||
Map_info | Map | III | Position | -25.7793 | Error | 0.003862 | |||
Positive | Positive_clone | B0412 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4251 | |||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00010874 | ||||||||
WBPaper00024524 | |||||||||
WBPaper00024671 | |||||||||
WBPaper00026952 | |||||||||
WBPaper00027309 | |||||||||
WBPaper00033137 | |||||||||
WBPaper00034843 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00065158 | |||||||||
Remark | ski-1 became an other-name of dac-1 as this locus encodes the C. elegans ortholog of Dachshund, rather than of the related protein SKI | Person_evidence | WBPerson473 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |