WormBase Tree Display for Gene: WBGene00000906
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WBGene00000906 | SMap | S_parent | Sequence | F23B2 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||
Name | CGC_name | daf-10 | Person_evidence | WBPerson521 | |||
WBPerson41163 | |||||||
Sequence_name | F23B2.4 | ||||||
Molecular_name | F23B2.4 | ||||||
F23B2.4.1 | |||||||
CE40504 | |||||||
Other_name | osm-4 | ||||||
ift-122 | Person_evidence | WBPerson41163 | |||||
CELE_F23B2.4 | Accession_evidence | NDB | BX284604 | ||||
Public_name | daf-10 | ||||||
DB_info | Database (12) | ||||||
Species | Caenorhabditis elegans | ||||||
History (2) | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | daf | ||||||
Reference_allele | WBVar00143964 | ||||||
Allele (124) | |||||||
Legacy_information | e1387 : defective dauer formation (daf-8 daf-2 suppressible) abnormal chemotaxis abnormal osmotic avoidance males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells cephalic neurons; octopamine deficient. ES1. ME0. NA2 (m79 p821 pka osm-4). | ||||||
See daf-10. | |||||||
See also e1387, p821 | |||||||
[C.elegansII] e1387 : defective dauer formation; abnormal chemotaxis abnormal osmotic avoidance; males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells, cephalic neurons; Dyf (FITC uptake defective); octopamine deficient. ES1. ME0. OA10: m79, p821 (pka osm-4), m534mut, mn321mut, etc. [Starich et al. 1995; DR; SP] | |||||||
Strain | WBStrain00030799 | ||||||
WBStrain00036760 | |||||||
WBStrain00004318 | |||||||
WBStrain00004878 | |||||||
WBStrain00006213 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (20) | |||||||
Ortholog (43) | |||||||
Structured_description | Concise_description | daf-10 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex A component IFT122; daf-10 activity is required for intraflagellar transport and thus for proper development of amphid and phasmid neurons, dauer development, chemotaxis, and normal lifespan; a DAF-10::GFP fusion protein undergoes both anterograde and retrograde intraflagellar transport in amphid or phasmid sensory neurons. | Paper_evidence | WBPaper00000503 | |||
WBPaper00001393 | |||||||
WBPaper00001482 | |||||||
WBPaper00002087 | |||||||
WBPaper00003835 | |||||||
WBPaper00004715 | |||||||
WBPaper00026822 | |||||||
WBPaper00027360 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 23 Feb 2007 00:00:00 | ||||||
Automated_description | Involved in several processes, including non-motile cilium assembly; positive regulation of dauer larval development; and receptor localization to non-motile cilium. Located in ciliary basal body. Human ortholog(s) of this gene implicated in cranioectodermal dysplasia 1. Is an ortholog of human IFT122 (intraflagellar transport 122). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0080803 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13556) | ||
Molecular_info | Corresponding_CDS | F23B2.4 | |||||
Corresponding_CDS_history | F23B2.4:wp164 | ||||||
F23B2.4:wp166 | |||||||
Corresponding_transcript | F23B2.4.1 | ||||||
Other_sequence (13) | |||||||
Associated_feature | WBsf652038 | ||||||
Experimental_info | RNAi_result | WBRNAi00098609 | Inferred_automatically | RNAi_primary | |||
WBRNAi00013805 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00098640 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00045391 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00098675 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00098722 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1015512 | ||||||
Expr1030569 | |||||||
Expr1149314 | |||||||
Expr2010760 | |||||||
Expr2028997 | |||||||
Drives_construct | WBCnstr00037204 | ||||||
Construct_product | WBCnstr00008557 | ||||||
WBCnstr00017221 | |||||||
WBCnstr00017229 | |||||||
WBCnstr00037204 | |||||||
Regulate_expr_cluster | WBPaper00041876:daf-10(m79)_downreglated | ||||||
WBPaper00041876:daf-10(m79)_upreglated | |||||||
Microarray_results (20) | |||||||
Expression_cluster (140) | |||||||
Interaction (32) | |||||||
Map_info | Map | IV | Position | 4.05374 | Error | 0.000504 | |
Well_ordered | |||||||
Positive | Positive_clone (2) | ||||||
Mapping_data | 2_point | 366 | |||||
367 | |||||||
429 | |||||||
430 | |||||||
Multi_point | 1125 | ||||||
3239 | |||||||
Reference (86) | |||||||
Method | Gene |