WormBase Tree Display for Gene: WBGene00000911
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| WBGene00000911 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | daf-15 | Person_evidence | WBPerson521 | |||||
| Sequence_name | C10C5.6 | ||||||||
| Molecular_name (15) | |||||||||
| Other_name | CELE_C10C5.6 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | daf-15 | ||||||||
| DB_info | Database | AceView | gene | 4K159 | |||||
| WormQTL | gene | WBGene00000911 | |||||||
| WormFlux | gene | WBGene00000911 | |||||||
| NDB | locus_tag | CELE_C10C5.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000911|UniProtKB=Q68TI8 | |||||||
| family | PTHR12848 | ||||||||
| NCBI | gene | 177770 | |||||||
| RefSeq | protein | NM_001306929.3 | |||||||
| NM_001306928.3 | |||||||||
| NM_069252.7 | |||||||||
| NM_001380409.1 | |||||||||
| NM_001392368.1 | |||||||||
| TREEFAM | TREEFAM_ID | TF105729 | |||||||
| TrEMBL | UniProtAcc | S6F588 | |||||||
| G5EEV7 | |||||||||
| G5EF88 | |||||||||
| Q68TI8 | |||||||||
| S6FD39 | |||||||||
| UniProt_GCRP | UniProtAcc | Q68TI8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 29 Sep 2004 13:15:37 | WBPerson1971 | Event | Acquires_merge | WBGene00007510 | ||||
| Acquires_merge | WBGene00007510 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | daf | ||||||||
| Reference_allele | WBVar00088570 | ||||||||
| Allele (97) | |||||||||
| Legacy_information | m81 : constitutive formation of abnormal dauer-like larvae irreversible (genetically lethal). ES3 (L3). NA1. | ||||||||
| [C.elegansII] m81 : constitutive formation of abnormal dauer-like larvae irreversible (genetically lethal); does not form true dauers in pheromone. ES3 (L3). OA7. [Albert and Riddle 1988; DR; JT] | |||||||||
| Strain | WBStrain00036259 | ||||||||
| WBStrain00006255 | |||||||||
| WBStrain00006256 | |||||||||
| WBStrain00006315 | |||||||||
| WBStrain00008445 | |||||||||
| WBStrain00047255 | |||||||||
| WBStrain00047253 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | daf-15 encodes an ortholog of RAPTOR (the regulatory associated proteinof mTOR), and is regulated by DAF-16; daf-15 is required for non-dauerdevelopment, at least in some tissues or stages; daf-15(m81) mutantsconstitutively and irreversibly form abnormal dauer-like larvae (and arethus effectively lethal/sterile); mutants do not form true dauers whenexposed to dauer pheromone, yet execute only two molts. | Paper_evidence | WBPaper00001035 | |||||
| WBPaper00014800 | |||||||||
| WBPaper00024450 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 04 Dec 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein kinase activator activity and protein-macromolecule adaptor activity. Involved in dauer larval development; determination of adult lifespan; and regulation of autophagosome assembly. Part of TORC1 complex. Expressed in several structures, including body wall musculature; excretory cell; hermaphrodite distal tip cell; intestine; and pharyngeal muscle cell. Is an ortholog of human RPTOR (regulatory associated protein of MTOR complex 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050742 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:30287) | ||||
| Molecular_info | Corresponding_CDS | C10C5.6a | |||||||
| C10C5.6b | |||||||||
| C10C5.6c | |||||||||
| C10C5.6d | |||||||||
| C10C5.6e | |||||||||
| Corresponding_CDS_history | C10C5.6a:wp57 | ||||||||
| C10C5.6b:wp57 | |||||||||
| Corresponding_transcript | C10C5.6a.1 | ||||||||
| C10C5.6b.1 | |||||||||
| C10C5.6c.1 | |||||||||
| C10C5.6d.1 | |||||||||
| C10C5.6e.1 | |||||||||
| Other_sequence (31) | |||||||||
| Associated_feature | WBsf646231 | ||||||||
| WBsf646232 | |||||||||
| WBsf660506 | |||||||||
| WBsf660507 | |||||||||
| WBsf997410 | |||||||||
| WBsf228824 | |||||||||
| WBsf228825 | |||||||||
| WBsf228826 | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr3426 | ||||||||
| Expr16310 | |||||||||
| Expr16311 | |||||||||
| Expr1023758 | |||||||||
| Expr1030572 | |||||||||
| Expr1144360 | |||||||||
| Expr2010764 | |||||||||
| Expr2029001 | |||||||||
| Drives_construct | WBCnstr00011393 | ||||||||
| WBCnstr00037200 | |||||||||
| Construct_product | WBCnstr00009134 | ||||||||
| WBCnstr00009135 | |||||||||
| WBCnstr00009136 | |||||||||
| WBCnstr00009137 | |||||||||
| WBCnstr00009140 | |||||||||
| WBCnstr00009141 | |||||||||
| WBCnstr00011393 | |||||||||
| WBCnstr00037200 | |||||||||
| Regulate_expr_cluster | WBPaper00064064:DAF-15_interacting | ||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (113) | |||||||||
| SAGE_tag (29) | |||||||||
| Interaction (74) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | IV | Position | 4.19361 | Error | 0.00315 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | mDp4 | |||||||
| Positive_clone | C10C5 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Mapping_data | 2_point | 438 | |||||||
| 439 | |||||||||
| 440 | |||||||||
| Multi_point (11) | |||||||||
| Pos_neg_data | 958 | ||||||||
| 963 | |||||||||
| 2734 | |||||||||
| 9115 | |||||||||
| Reference (53) | |||||||||
| Method | Gene |
