WormBase Tree Display for Gene: WBGene00001160
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| WBGene00001160 | SMap | S_parent | Sequence | F42A10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | efk-1 | Person_evidence | WBPerson145 | |||||
| Sequence_name | F42A10.4 | ||||||||
| Molecular_name | F42A10.4a | ||||||||
| F42A10.4a.1 | |||||||||
| CE32415 | |||||||||
| F42A10.4b | |||||||||
| CE32416 | |||||||||
| F42A10.4b.1 | |||||||||
| Other_name | efk1 | Accession_evidence | EMBL | U93846 | |||||
| U93847 | |||||||||
| CELE_F42A10.4 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | efk-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | efk | ||||||||
| Allele (53) | |||||||||
| Legacy_information | [Ryazanov AG] efk for Elongation Factor Kinase. No mutants known. Encodes EFK-1A and EFK-1B, two products produced by alternative splicing, EFK-1B omits exon IV. C. elegans homolog of mammalian elongation factor-2 kinase (eEF-2 kinase). | ||||||||
| Strain | WBStrain00033263 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOP3900 | ||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | efk-1 encodes a calcium/calmodulin-dependent protein kinase with homology to human elongation factor-2 kinase; expressed in only a few cells in embryos. | Paper_evidence | WBPaper00002841 | |||||
| WBPaper00017814 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables elongation factor-2 kinase activity. Predicted to be involved in myosin II filament disassembly. Human ortholog(s) of this gene implicated in Alzheimer's disease and lung adenocarcinoma. Is an ortholog of human EEF2K (eukaryotic elongation factor 2 kinase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:24615) | ||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:24615) | ||||||
| Molecular_info | Corresponding_CDS | F42A10.4a | |||||||
| F42A10.4b | |||||||||
| Corresponding_CDS_history | F42A10.4a:wp88 | ||||||||
| F42A10.4b:wp88 | |||||||||
| Corresponding_transcript | F42A10.4a.1 | ||||||||
| F42A10.4b.1 | |||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf666972 | ||||||||
| WBsf226772 | |||||||||
| WBsf226773 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00005317 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00014792 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047057 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115388 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00097655 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000356 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027708 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098182 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2042 | ||||||||
| Expr1014472 | |||||||||
| Expr1030738 | |||||||||
| Expr1150920 | |||||||||
| Expr2011188 | |||||||||
| Expr2029424 | |||||||||
| Drives_construct | WBCnstr00037056 | ||||||||
| Construct_product | WBCnstr00037056 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (51) | |||||||||
| Map_info | Map | III | Position | -1.41114 | Error | 0.000417 | |||
| Positive | Positive_clone | F42A10 | Person_evidence | WBPerson5884 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | See Ryazanov et al. (1997) | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
