WormBase Tree Display for Gene: WBGene00001345
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| WBGene00001345 | SMap | S_parent | Sequence | F29G9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | fos-1 | Person_evidence | WBPerson625 | |||||
| Sequence_name | F29G9.4 | ||||||||
| Molecular_name | F29G9.4a | ||||||||
| F29G9.4a.1 | |||||||||
| CE27375 | |||||||||
| F29G9.4b | |||||||||
| CE39151 | |||||||||
| F29G9.4a.2 | |||||||||
| F29G9.4a.3 | |||||||||
| F29G9.4a.4 | |||||||||
| F29G9.4a.5 | |||||||||
| F29G9.4b.1 | |||||||||
| Other_name | evl-5 | Person_evidence | WBPerson220 | ||||||
| CELE_F29G9.4 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | fos-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00001345 | |||||
| WormFlux | gene | WBGene00001345 | |||||||
| NDB | locus_tag | CELE_F29G9.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001345|UniProtKB=G5ECG2 | |||||||
| family | PTHR23351 | ||||||||
| NCBI | gene | 178987 | |||||||
| RefSeq | protein | NM_001392524.1 | |||||||
| NM_001038392.5 | |||||||||
| SwissProt | UniProtAcc | G5ECG2 | |||||||
| TREEFAM | TREEFAM_ID | TF315954 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECG2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 27 Sep 2005 15:14:58 | WBPerson2970 | Event | Acquires_merge | WBGene00017932 | ||||
| Name_change | CGC_name | fos-1 | |||||||
| Other_name | evl-5 | ||||||||
| Acquires_merge | WBGene00017932 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fos | ||||||||
| Allele (184) | |||||||||
| Legacy_information | [C.elegansII] ar105 : everted vulva, sterile; abnormal L4 vulval invagination, abnormal uterus, abnormal oocytes. NA1. [Seydoux et al., 1993] | ||||||||
| Strain | WBStrain00008001 | ||||||||
| WBStrain00034962 | |||||||||
| WBStrain00047251 | |||||||||
| WBStrain00054725 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (39) | |||||||||
| Ortholog (26) | |||||||||
| Paralog | WBGene00021082 | Caenorhabditis elegans | From_analysis | Panther | |||||
| Structured_description | Concise_description | fos-1 encodes two basic region-leucine zipper (bZip) transcription factors, FOS-1A and FOS-1B, that are the sole C. elegans orthologs of the fos bZip transcription factor family; during hermaphrodite development, FOS-1A activity is required cell autonomously in the gonadal anchor cell for basement-membrane removal and subsequent anchor cell invasion of the vulval epithelium; in addition, fos-1 activity is also required for proper vulval and uterine development, fertility, and oogenesis; in late-L3 larvae, a FOS-1A translational fusion protein is expressed at high levels in the anchor cell nucleus and at lower levels in uterine cells, while a FOS-1B reporter is expressed at low levels in the anchor cell, uterine, and vulval cells; transcriptional reporters additionally reveal that fos-1b is expressed in most cells of late L3 larvae; in affecting anchor cell invasion, FOS-1A appears to act by regulating the expression of three AC-expressed genes: cdh-3/cadherin, him-4/hemicentin, and zmp-1/matrix metalloproteinase, which likely function together to promote anchor cell invasion. | Paper_evidence | WBPaper00001738 | |||||
| WBPaper00026611 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 23 Feb 2006 00:00:00 | ||||||||
| Automated_description | Enables several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and identical protein binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of stress response to copper ion; and regulation of gene expression. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including gonad; neurons; uterine pi cell; ventral uterine precursor; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F29G9.4a | |||||||
| F29G9.4b | |||||||||
| Corresponding_transcript | F29G9.4a.1 | ||||||||
| F29G9.4a.2 | |||||||||
| F29G9.4a.3 | |||||||||
| F29G9.4a.4 | |||||||||
| F29G9.4a.5 | |||||||||
| F29G9.4b.1 | |||||||||
| Other_sequence (15) | |||||||||
| Associated_feature (20) | |||||||||
| Gene_product_binds (15126) | |||||||||
| Transcription_factor | WBTranscriptionFactor000109 | ||||||||
| WBTranscriptionFactor000125 | |||||||||
| WBTranscriptionFactor000252 | |||||||||
| WBTranscriptionFactor000253 | |||||||||
| Experimental_info | RNAi_result (43) | ||||||||
| Expr_pattern (13) | |||||||||
| Drives_construct (13) | |||||||||
| Construct_product | WBCnstr00004687 | ||||||||
| WBCnstr00016617 | |||||||||
| WBCnstr00016732 | |||||||||
| WBCnstr00018205 | |||||||||
| WBCnstr00036991 | |||||||||
| Antibody | WBAntibody00002407 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (157) | |||||||||
| Interaction (44) | |||||||||
| Anatomy_function | WBbtf0418 | ||||||||
| Product_binds_matrix | WBPmat00005559 | ||||||||
| WBPmat00005579 | |||||||||
| Map_info | Map | V | Position | -0.462278 | Error | 0.00249 | |||
| Positive | Positive_clone | F29G9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 3488 | |||||||
| 3489 | |||||||||
| Reference (54) | |||||||||
| Method | Gene |
