WormBase Tree Display for Gene: WBGene00001477
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WBGene00001477 | SMap | S_parent | Sequence | K08C7 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | fmo-2 | |||||||
Sequence_name | K08C7.5 | ||||||||
Molecular_name | K08C7.5 | ||||||||
K08C7.5.1 | |||||||||
CE06138 | |||||||||
Other_name | fmo-12 | Person_evidence | WBPerson3011 | ||||||
CELE_K08C7.5 | Accession_evidence | NDB | BX284604 | ||||||
Public_name | fmo-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 20 Sep 2004 14:56:48 | WBPerson1971 | Name_change | CGC_name | fmo-12 -> fmo-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | fmo | ||||||||
Allele (31) | |||||||||
Strain | WBStrain00036780 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (20) | |||||||||
Ortholog (60) | |||||||||
Paralog | WBGene00001476 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001478 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001480 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001479 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00007254 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00016728 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | fmo-2 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria). | Paper_evidence | WBPaper00004637 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 16 May 2007 00:00:00 | ||||||||
Automated_description | Enables monooxygenase activity. Involved in defense response to Gram-negative bacterium and one-carbon metabolic process. Located in cytoplasm. Expressed in excretory gland cell; head; intestinal cell; intestine; and neurons. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0080361 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3771) | ||||
DOID:655 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3771) | ||||||
DOID:10763 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3771) | ||||||
Molecular_info | Corresponding_CDS | K08C7.5 | |||||||
Corresponding_transcript | K08C7.5.1 | ||||||||
Other_sequence | JI211760.1 | ||||||||
FK804404.1 | |||||||||
HGC03431_1 | |||||||||
BXC00339_1 | |||||||||
CBC02134_1 | |||||||||
EX538053.1 | |||||||||
ACC11537_1 | |||||||||
Associated_feature | WBsf646324 | ||||||||
WBsf646325 | |||||||||
WBsf997676 | |||||||||
WBsf1018126 | |||||||||
WBsf229021 | |||||||||
WBsf229022 | |||||||||
Experimental_info | RNAi_result | WBRNAi00050238 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00034110 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00001310 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00098157 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00061320 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00092239 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00016781 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3218 | ||||||||
Expr12637 | |||||||||
Expr13705 | |||||||||
Expr15841 | |||||||||
Expr16306 | |||||||||
Expr1020750 | |||||||||
Expr1153933 | |||||||||
Expr2011857 | |||||||||
Expr2030095 | |||||||||
Drives_construct | WBCnstr00011229 | ||||||||
WBCnstr00022344 | |||||||||
WBCnstr00022519 | |||||||||
WBCnstr00036921 | |||||||||
WBCnstr00039947 | |||||||||
WBCnstr00042554 | |||||||||
WBCnstr00042889 | |||||||||
Construct_product | WBCnstr00022344 | ||||||||
WBCnstr00036921 | |||||||||
WBCnstr00039634 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (314) | |||||||||
Interaction (20) | |||||||||
Map_info | Map | IV | Position | 4.66268 | Error | 0.004734 | |||
Positive | Positive_clone | K08C7 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4245 | |||||||
4322 | |||||||||
4321 | |||||||||
Pseudo_map_position | |||||||||
Reference (29) | |||||||||
Remark | Sequence connection from [Barstead RJ] [040902 ck1] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
This gene has been renamed with approval of the CGC (fmo-12->fmo-2) | Person_evidence | WBPerson3011 | |||||||
Method | Gene |