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WormBase Tree Display for Gene: WBGene00001477

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Name Class

WBGene00001477SMapS_parentSequenceK08C7
IdentityVersion2
NameCGC_namefmo-2
Sequence_nameK08C7.5
Molecular_nameK08C7.5
K08C7.5.1
CE06138
Other_namefmo-12Person_evidenceWBPerson3011
CELE_K08C7.5Accession_evidenceNDBBX284604
Public_namefmo-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 14:56:48WBPerson1971Name_changeCGC_namefmo-12 -> fmo-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfmo
Allele (31)
StrainWBStrain00036780
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (60)
ParalogWBGene00001476Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001478Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001480Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001479Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007254Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016728Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionfmo-2 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria).Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson567
Date_last_updated16 May 2007 00:00:00
Automated_descriptionEnables monooxygenase activity. Involved in defense response to Gram-negative bacterium and one-carbon metabolic process. Located in cytoplasm. Expressed in excretory gland cell; head; intestinal cell; intestine; and neurons. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080361Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
DOID:655Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
DOID:10763Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3771)
Molecular_infoCorresponding_CDSK08C7.5
Corresponding_transcriptK08C7.5.1
Other_sequenceJI211760.1
FK804404.1
HGC03431_1
BXC00339_1
CBC02134_1
EX538053.1
ACC11537_1
Associated_featureWBsf646324
WBsf646325
WBsf997676
WBsf1018126
WBsf229021
WBsf229022
Experimental_infoRNAi_resultWBRNAi00050238Inferred_automaticallyRNAi_primary
WBRNAi00034110Inferred_automaticallyRNAi_primary
WBRNAi00001310Inferred_automaticallyRNAi_primary
WBRNAi00098157Inferred_automaticallyRNAi_primary
WBRNAi00061320Inferred_automaticallyRNAi_primary
WBRNAi00092239Inferred_automaticallyRNAi_primary
WBRNAi00016781Inferred_automaticallyRNAi_primary
Expr_patternExpr3218
Expr12637
Expr13705
Expr15841
Expr16306
Expr1020750
Expr1153933
Expr2011857
Expr2030095
Drives_constructWBCnstr00011229
WBCnstr00022344
WBCnstr00022519
WBCnstr00036921
WBCnstr00039947
WBCnstr00042554
WBCnstr00042889
Construct_productWBCnstr00022344
WBCnstr00036921
WBCnstr00039634
Microarray_results (18)
Expression_cluster (314)
Interaction (20)
Map_infoMapIVPosition4.66268Error0.004734
PositivePositive_cloneK08C7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4245
4322
4321
Pseudo_map_position
Reference (29)
RemarkSequence connection from [Barstead RJ] [040902 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
This gene has been renamed with approval of the CGC (fmo-12->fmo-2)Person_evidenceWBPerson3011
MethodGene