WormBase Tree Display for Gene: WBGene00001593
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WBGene00001593 | SMap | S_parent | Sequence | ZC317 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | glc | ||||||
Allele (77) | |||||||
Strain | WBStrain00003302 | ||||||
WBStrain00031369 | |||||||
WBStrain00040635 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (21) | |||||||
Ortholog (45) | |||||||
Paralog (100) | |||||||
Structured_description | Concise_description | glc-3 encodes an L-glutamate-gated chloride channel subunit; GLC-3 is sensitive to fipronil and BIDN, but picrotoxinin-insensitive; GLC-3 is expressed in the AIY interneuron. | Paper_evidence | WBPaper00004607 | |||
WBPaper00024232 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 02 Sep 2011 00:00:00 | ||||||
Automated_description | Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Involved in locomotion involved in locomotory behavior; sensory perception of chemical stimulus; and sensory processing. Predicted to be located in neuron projection and synapse. Expressed in M4 neuron; head ganglion; and tail neurons. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0070422 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4327) | ||
DOID:0060696 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4326) | ||||
Molecular_info | Corresponding_CDS | ZC317.3 | |||||
Corresponding_transcript | ZC317.3.1 | ||||||
Other_sequence (31) | |||||||
Associated_feature | WBsf668950 | ||||||
WBsf668951 | |||||||
WBsf1000006 | |||||||
WBsf1000007 | |||||||
WBsf1019634 | |||||||
WBsf1019635 | |||||||
WBsf233679 | |||||||
Experimental_info | RNAi_result | WBRNAi00030288 | Inferred_automatically | RNAi_primary | |||
WBRNAi00021651 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00058833 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr7157 | ||||||
Expr10073 | |||||||
Expr12054 | |||||||
Expr15365 | |||||||
Expr15923 | |||||||
Expr15925 | |||||||
Expr1016872 | |||||||
Expr1162269 | |||||||
Expr2012081 | |||||||
Expr2030317 | |||||||
Drives_construct | WBCnstr00003773 | ||||||
WBCnstr00015045 | |||||||
WBCnstr00036839 | |||||||
WBCnstr00042608 | |||||||
Construct_product (11) | |||||||
Microarray_results (17) | |||||||
Expression_cluster (123) | |||||||
Interaction (20) | |||||||
Map_info | Map | V | Position | -1.89496 | Error | 0.015231 | |
Positive | Positive_clone | ZC317 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4348 | |||||
Pseudo_map_position | |||||||
Reference (24) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |