WormBase Tree Display for Gene: WBGene00001618

WBGene00001618 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: glr-7 Person_evidence: WBPerson42
      Sequence_name: C43H6.9
      Molecular_name: C43H6.9a
        C43H6.9a.1
        CE41776
        C43H6.9b
        CE51946
        C43H6.9a.2
        C43H6.9b.1
      Other_name: CELE_C43H6.9 Accession_evidence: NDB BX284606
      Public_name: glr-7
    DB_info: Database: AceView gene XD34
        WormQTL gene WBGene00001618
        WormFlux gene WBGene00001618
        NDB locus_tag CELE_C43H6.9
        Panther gene CAEEL|WormBase=WBGene00001618|UniProtKB=A0A1T5HUM0
          family PTHR18966
        NCBI gene 180547
        RefSeq protein NM_001373243.1
            NM_001350348.3
        TrEMBL UniProtAcc A0A1T5HUM0
            Q18591
        UniProt_GCRP UniProtAcc A0A1T5HUM0
        OMIM gene 602368
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 03 Mar 2017 00:18:26 WBPerson1983 Event: Acquires_merge: WBGene00020303
      Acquires_merge: WBGene00020303
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: glr
    Allele (81)
    RNASeq_FPKM (74)
    GO_annotation (18)
    Contained_in_operon: CEOPX032
    Ortholog (39)
    Paralog: WBGene00001612 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001613 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001614 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001615 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001616 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001617 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001619 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003774 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003775 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012190 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: glr-7 encodes a protein containing a ligand-gated ion channel domain and is a predicted non-NMDA type ionotropic glutamate receptor; expressed in the pharyngeal nervous system. Paper_evidence: WBPaper00004567
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 18. Is an ortholog of human GRID1 (glutamate ionotropic receptor delta type subunit 1) and GRID2 (glutamate ionotropic receptor delta type subunit 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080042 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4576)
  Molecular_info: Corresponding_CDS: C43H6.9a
      C43H6.9b
    Corresponding_CDS_history: C43H6.9:wp92
      C43H6.9:wp184
      C43H6.9c:wp271
    Corresponding_transcript: C43H6.9a.1
      C43H6.9a.2
      C43H6.9b.1
    Other_sequence (19)
    Associated_feature: WBsf653744
  Experimental_info: RNAi_result: WBRNAi00102728 Inferred_automatically: RNAi_primary
      WBRNAi00042408 Inferred_automatically: RNAi_primary
      WBRNAi00052745 Inferred_automatically: RNAi_primary
      WBRNAi00023087 Inferred_automatically: RNAi_primary
      WBRNAi00065702 Inferred_automatically: RNAi_primary
      WBRNAi00018357 Inferred_automatically: RNAi_primary
      WBRNAi00011902 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr822
      Expr1015272
      Expr1022370
      Expr1146397
      Expr1156352
      Expr2012118
      Expr2030354
    Drives_construct: WBCnstr00005003
      WBCnstr00013189
      WBCnstr00042861
    Construct_product: WBCnstr00013189
      WBCnstr00015868
    Microarray_results (31)
    Expression_cluster (84)
    Interaction (14)
  Map_info: Map: X Position: -15.5364 Error: 0.012291
    Positive: Positive_clone: C43H6 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Sequence connection from [Brockie PJ, Maricq AV, Aronoff R], 02/06/11 krb.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene