WormBase Tree Display for Gene: WBGene00001696
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WBGene00001696 | Evidence | Paper_evidence | WBPaper00003717 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F46H5 | ||||
Identity | Version | 2 | |||||
Name | CGC_name | grd-7 | Person_evidence | WBPerson83 | |||
Sequence_name | F46H5.6 | ||||||
Molecular_name | F46H5.6 | ||||||
F46H5.6.1 | |||||||
CE10614 | |||||||
Other_name | CELE_F46H5.6 | Accession_evidence | NDB | BX284606 | |||
Public_name | grd-7 | ||||||
DB_info | Database | AceView | gene | XH886 | |||
WormQTL | gene | WBGene00001696 | |||||
WormFlux | gene | WBGene00001696 | |||||
NDB | locus_tag | CELE_F46H5.6 | |||||
NCBI | gene | 191661 | |||||
RefSeq | protein | NM_076823.5 | |||||
TREEFAM | TREEFAM_ID | TF316390 | |||||
TrEMBL | UniProtAcc | Q3Y407 | |||||
UniProt_GCRP | UniProtAcc | Q3Y407 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Split_into | WBGene00303398 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | grd | ||||||
Allele (41) | |||||||
Strain | WBStrain00033131 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00080704 | ||||||
00080705 | |||||||
00080706 | |||||||
00080707 | |||||||
00080708 | |||||||
Ortholog (13) | |||||||
Paralog (30) | |||||||
Structured_description | Concise_description | grd-7 encodes a hedgehog-like protein, with an N-terminal DUF271 domain,a central low-complexity proline-rich domain, and a C-terminal Ground(Grd) domain; GRD-7 is expressed in three to four posterior DA motorneurons of the ventral nerve cord; the Ground domain is predicted toform a cysteine-crosslinked protein involved in intercellularsignalling, and it has subtle similarity to the N-terminal Hedge domainof HEDGEHOG proteins; GRD-7 is weakly required for normal molting; GRD-7is also required for normal growth to full size, cuticle adhesion,locomotion, and vulval morphogenesis; all of these requirements mayreflect common defects in cholesterol-dependent hedgehog-like signallingor in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||
WBPaper00003717 | |||||||
WBPaper00026841 | |||||||
WBPaper00027263 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||
Automated_description | Predicted to enable signaling receptor binding activity. Predicted to be involved in cell communication. Predicted to be located in extracellular region. Expressed in seam cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F46H5.6 | |||||
Corresponding_CDS_history | F46H5.6:wp133 | ||||||
F46H5.6:wp204 | |||||||
F46H5.6:wp266 | |||||||
Corresponding_transcript | F46H5.6.1 | ||||||
Other_sequence | AS01157 | ||||||
AS01829 | |||||||
AS00174 | |||||||
JO473146.1 | |||||||
Associated_feature | WBsf654124 | ||||||
WBsf670714 | |||||||
Experimental_info | RNAi_result | WBRNAi00076996 | Inferred_automatically | RNAi_primary | |||
WBRNAi00047583 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00032397 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00077020 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr638 | ||||||
Expr4433 | |||||||
Expr1016250 | |||||||
Expr1151420 | |||||||
Expr2012237 | |||||||
Expr2030473 | |||||||
Drives_construct | WBCnstr00011996 | ||||||
WBCnstr00012462 | |||||||
WBCnstr00036760 | |||||||
Construct_product | WBCnstr00036760 | ||||||
Microarray_results (14) | |||||||
Expression_cluster (68) | |||||||
Interaction | WBInteraction000454627 | ||||||
WBInteraction000523707 | |||||||
WBInteraction000546242 | |||||||
WBInteraction000546430 | |||||||
WBInteraction000546604 | |||||||
WBInteraction000546814 | |||||||
WBInteraction000548120 | |||||||
WBInteraction000548121 | |||||||
WBInteraction000548122 | |||||||
WBProcess | WBbiopr:00000123 | ||||||
Map_info | Map | X | Position | -1.78652 | Error | 0.001722 | |
Positive | Positive_clone | F46H5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00002823 | ||||||
WBPaper00003717 | |||||||
WBPaper00011801 | |||||||
WBPaper00024393 | |||||||
WBPaper00026841 | |||||||
WBPaper00028754 | |||||||
WBPaper00031588 | |||||||
WBPaper00064105 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |