WormBase Tree Display for Gene: WBGene00001811

WBGene00001811 SMap: S_parent: Sequence: C30H6
  Identity: Version: 1
    Name: CGC_name: haf-1 Person_evidence: WBPerson36
      Sequence_name: C30H6.6
      Molecular_name: C30H6.6
        C30H6.6.1
        CE39331
      Other_name: CELE_C30H6.6 Accession_evidence: NDB BX284604
      Public_name: haf-1
    DB_info: Database: AceView gene 4S321
        WormQTL gene WBGene00001811
        WormFlux gene WBGene00001811
        NDB locus_tag CELE_C30H6.6
        Panther gene CAEEL|WormBase=WBGene00001811|UniProtKB=O45278
          family PTHR24221
        NCBI gene 178522
        RefSeq protein NM_070697.7
        TREEFAM TREEFAM_ID TF105198
        TrEMBL UniProtAcc O45278
        UniProt_GCRP UniProtAcc O45278
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: haf
    Allele (110)
    Strain: WBStrain00031580
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (39)
    Paralog (23)
    Structured_description: Concise_description: haf-1 encodes a transmembrane protein that is a member of the ATP-binding cassette (ABC) transporter superfamily; HAF-1 transporter activity is required for peptide transport and functions as part of the mitochondrial unfolded protein response (UPRmt) signaling pathway; as part of the UPRmt, HAF-1 functions upstream of the ATFS-1 bZip transcription factor that partitions between the mitochondrion, where it is degraded under normal conditions, and the nucleus, where it localizes in response to the UPRmt; HAF-1 localizes to the the inner mitochondrial membrane. Paper_evidence: WBPaper00035985
          Curator_confirmed: WBPerson1843
          Date_last_updated: 23 Oct 2012 00:00:00
      Automated_description: Enables peptide transmembrane transporter activity. Involved in mitochondrial unfolded protein response; peptide transport; and protein import into mitochondrial matrix. Located in mitochondrial inner membrane. Is an ortholog of human ABCB10 (ATP binding cassette subfamily B member 10). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C30H6.6
    Corresponding_CDS_history: C30H6.6:wp151
    Corresponding_transcript: C30H6.6.1
    Other_sequence: DVC03108_1
      Dviv_isotig16313
      Dviv_isotig16312
      EV853081.1
      CBC16086_1
    Associated_feature: WBsf229635
  Experimental_info: RNAi_result: WBRNAi00011409 Inferred_automatically: RNAi_primary
      WBRNAi00029369 Inferred_automatically: RNAi_primary
      WBRNAi00041579 Inferred_automatically: RNAi_primary
      WBRNAi00113844 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3353
      Expr1023833
      Expr1031060
      Expr1145603
      Expr2012355
      Expr2030591
    Drives_construct: WBCnstr00011350
      WBCnstr00018526
      WBCnstr00036673
    Construct_product: WBCnstr00036673
    Microarray_results (19)
    Expression_cluster (91)
    Interaction (43)
    WBProcess: WBbiopr:00000077
      WBbiopr:00000079
  Map_info: Map: IV Position: 16.5892 Error: 0.027657
    Positive: Positive_clone: C30H6 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4778
    Pseudo_map_position
  Reference (24)
  Remark: Sequence connection from Sheps JA and Baillie DL [021008 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene