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WormBase Tree Display for Gene: WBGene00001814

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Name Class

WBGene00001814SMapS_parentSequenceW04C9
IdentityVersion1
NameCGC_namehaf-4Person_evidenceWBPerson36
Sequence_nameW04C9.1
Molecular_nameW04C9.1a
W04C9.1a.1
CE28355
W04C9.1b
CE49215
W04C9.1b.1
Other_nameCELE_W04C9.1Accession_evidenceNDBBX284601
Public_namehaf-4
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhaf
Allele (144)
StrainWBStrain00001134
WBStrain00002742
WBStrain00031784
WBStrain00035778
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (35)
Paralog (23)
Structured_descriptionConcise_descriptionhaf-4 encodes a half-molecular ATP-binding cassette (ABC) transporters similar to the conserved half-type ATP-binding cassette (ABC) transporter, TAPL/ABCB9; in elegans, haf-4 along with another TAPL gene, haf-9 is required for the formation of intestinal organelles; haf-4 and haf-9 are required for proper growth, normal brood size and for the normal defecation cycle; haf-4 and haf-9 are localized to intestinal organelles and physically interact to form a heterodimer.Paper_evidenceWBPaper00028970
WBPaper00033097
WBPaper00042080
Curator_confirmedWBPerson48
WBPerson1843
WBPerson324
Date_last_updated09 Sep 2013 00:00:00
Automated_descriptionPredicted to enable ATPase-coupled transmembrane transporter activity. Involved in lipid metabolic process and lysosomal transport. Located in lysosomal membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bronchial disease (multiple); and lung disease (multiple). Is an ortholog of human ABCB9 (ATP binding cassette subfamily B member 9).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSW04C9.1a
W04C9.1b
Corresponding_CDS_historyW04C9.1b:wp124
Corresponding_transcriptW04C9.1a.1
W04C9.1b.1
Other_sequence (48)
Associated_featureWBsf643014
WBsf655845
WBsf217135
Experimental_infoRNAi_resultWBRNAi00026481Inferred_automaticallyRNAi_primary
WBRNAi00004419Inferred_automaticallyRNAi_primary
WBRNAi00021246Inferred_automaticallyRNAi_primary
WBRNAi00026480Inferred_automaticallyRNAi_primary
WBRNAi00069350Inferred_automaticallyRNAi_primary
WBRNAi00091096Inferred_automaticallyRNAi_primary
WBRNAi00069351Inferred_automaticallyRNAi_primary
WBRNAi00054758Inferred_automaticallyRNAi_primary
Expr_pattern (12)
Drives_constructWBCnstr00002016
WBCnstr00002017
WBCnstr00003273
WBCnstr00011343
WBCnstr00011915
WBCnstr00013652
Construct_productWBCnstr00013652
AntibodyWBAntibody00001952
WBAntibody00002421
Microarray_results (23)
Expression_cluster (227)
Interaction (75)
Map_infoMapIPosition-18.9981Error0.007263
PositivePositive_cloneW04C9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4391
4732
5001
Pseudo_map_position
Reference (22)
RemarkSequence connection from Sheps JA and Baillie DL [021008 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene