WormBase Tree Display for Gene: WBGene00001965
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WBGene00001965 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C17C3 | ||||||
Identity | Version | 1 | |||||||
Name (5) | |||||||||
DB_info | Database | AceView | gene | 2F822 | |||||
WormQTL | gene | WBGene00001965 | |||||||
WormFlux | gene | WBGene00001965 | |||||||
NDB | locus_tag | CELE_C17C3.8 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001965|UniProtKB=Q18053 | |||||||
family | PTHR10985 | ||||||||
NCBI | gene | 173939 | |||||||
RefSeq | protein | NM_062661.7 | |||||||
SwissProt | UniProtAcc | Q18053 | |||||||
TREEFAM | TREEFAM_ID | TF322171 | |||||||
UniProt_GCRP | UniProtAcc | Q18053 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | hlh | ||||||||
Allele (21) | |||||||||
Strain | WBStrain00032036 | ||||||||
WBStrain00033856 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (11) | |||||||||
Ortholog (17) | |||||||||
Paralog | WBGene00001964 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00001968 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00001967 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00001966 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | hlh-26 encodes a REF-1-like protein with two bHLH domains that represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28) and tbx-37 transcription in EMS descendants (independently of Notch, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28); lag-2 repression by HLH-26 may require UNC-37; HLH-26's paralogs include HLH-25 through HLH-29 and (more distantly) REF-1; HLH-26 is not visibly expressed in EMS descendants, and has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00025235 | |||||
WBPaper00031196 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 18 Apr 2008 00:00:00 | ||||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ABpla; ABplp; ABpra; and ABprp. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C17C3.8 | |||||||
Corresponding_transcript | C17C3.8.1 | ||||||||
Associated_feature | WBsf978584 | ||||||||
Transcription_factor | WBTranscriptionFactor000073 | ||||||||
Experimental_info | RNAi_result | WBRNAi00084010 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00028995 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00040786 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00022289 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00107447 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8069 | ||||||||
Expr10328 | |||||||||
Expr10329 | |||||||||
Expr1017022 | |||||||||
Expr1144825 | |||||||||
Expr2012501 | |||||||||
Expr2030740 | |||||||||
Drives_construct | WBCnstr00005216 | ||||||||
WBCnstr00015259 | |||||||||
WBCnstr00036555 | |||||||||
Construct_product | WBCnstr00005216 | ||||||||
WBCnstr00036555 | |||||||||
Regulate_expr_cluster | WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium | ||||||||
WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium | |||||||||
Microarray_results (17) | |||||||||
Expression_cluster (47) | |||||||||
Interaction (145) | |||||||||
Map_info | Map | II | Position | -1.19632 | Error | 0.002366 | |||
Positive | Positive_clone | C17C3 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00025235 | ||||||||
WBPaper00027287 | |||||||||
WBPaper00027309 | |||||||||
WBPaper00029033 | |||||||||
WBPaper00030887 | |||||||||
WBPaper00031196 | |||||||||
WBPaper00034761 | |||||||||
WBPaper00062585 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |