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WormBase Tree Display for Gene: WBGene00002041

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Name Class

WBGene00002041SMapS_parentSequenceY66H1A
IdentityVersion1
NameCGC_namehum-8
Sequence_nameY66H1A.6
Molecular_nameY66H1A.6a
Y66H1A.6a.1
CE48936
Y66H1A.6c
CE48797
Y66H1A.6c.1
Other_nameCELE_Y66H1A.6Accession_evidenceNDBBX284604
Public_namehum-8
DB_infoDatabaseAceViewgene4B182
WormQTLgeneWBGene00002041
WormFluxgeneWBGene00002041
NDBlocus_tagCELE_Y66H1A.6
PanthergeneCAEEL|WormBase=WBGene00002041|UniProtKB=U4PBY2
familyPTHR13140
NCBIgene176872
RefSeqproteinNM_001307645.3
NM_001028377.5
TrEMBLUniProtAccH2L0I7
U4PBY2
UniProt_GCRPUniProtAccU4PBY2
OMIMgene600970
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhum
Allele (177)
Legacy_information[Titus MA] hum: heavy chain of an unconventional myosin hum-8 encodees a class VI unconventional myosin that is closely related to HUM-3
StrainWBStrain00032557
WBStrain00049468
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (40)
Paralog (21)
Structured_descriptionAutomated_descriptionPredicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization; endocytosis; and vesicle transport along actin filament. Predicted to be located in actin cytoskeleton and endocytic vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in auditory system disease (multiple) and reproductive organ cancer (multiple). Is an ortholog of human MYO6 (myosin VI).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110495Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7605)
DOID:10283Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7605)
DOID:10003Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7605)
DOID:0110552Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7605)
DOID:2394Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7605)
Molecular_infoCorresponding_CDSY66H1A.6a
Y66H1A.6c
Corresponding_CDS_historyY66H1A.6:wp126
Y66H1A.6a:wp239
Y66H1A.6b:wp154
Y66H1A.6b:wp239
Y66H1A.6b:wp271
Corresponding_transcriptY66H1A.6a.1
Y66H1A.6c.1
Other_sequence (11)
Associated_featureWBsf667719
WBsf667720
WBsf667721
WBsf667722
WBsf995143
Experimental_infoRNAi_resultWBRNAi00037719Inferred_automaticallyRNAi_primary
WBRNAi00080591Inferred_automaticallyRNAi_primary
WBRNAi00021255Inferred_automaticallyRNAi_primary
WBRNAi00057961Inferred_automaticallyRNAi_primary
Expr_patternExpr1024836
Expr1161388
Expr2012650
Expr2030886
Microarray_results (23)
Expression_cluster (160)
Interaction (38)
Map_infoMapIVPosition-25.9969Error0.006592
PositivePositive_cloneY66H1APerson_evidenceWBPerson658
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5489
Pseudo_map_position
ReferenceWBPaper00023304
WBPaper00024200
WBPaper00025258
WBPaper00038491
WBPaper00055090
WBPaper00064057
WBPaper00064860
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene