WormBase Tree Display for Gene: WBGene00002228
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WBGene00002228 | SMap | S_parent | Sequence | C06G3 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | klp | ||||||
Allele (45) | |||||||
Strain | WBStrain00036968 | ||||||
WBStrain00007392 | |||||||
WBStrain00049767 | |||||||
WBStrain00049537 | |||||||
WBStrain00049796 | |||||||
WBStrain00049736 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (19) | |||||||
Ortholog (42) | |||||||
Paralog (20) | |||||||
Structured_description | Concise_description | klp-18 encodes a kinesin motor protein whose motor domain is most similar to that of the Xenopus and human klp2 proteins; loss of klp-18 activity via RNAi indicates that KLP-18 is required for the assembly of a disordered array of acentrosomal (female meiotic) microtubules into an organized, functional, bipolar spindle; in addition, KLP-18 may also play a role in cortex dynamics during post-meiotic development; antibody staining indicates that during meiosis and mitosis (early embryonic) KLP-18 localizes to: 1) spindles, and especially spindle poles, during prometaphase, metaphase, and early anaphase, and 2) the interzone during late anaphase and telophase; in early embryos, KLP-18 is also seen around the nucleus and cell cortex at sites of cell-cell contact; KLP-18 expression in later embryos and larvae is confined to the germ line which, in adults, stains brightly in both distal and proximal regions. | Paper_evidence | WBPaper00006197 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 15 Nov 2005 00:00:00 | ||||||
Automated_description | Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic spindle assembly. Located in cell cortex; microtubule; and spindle pole. Expressed in Z2; Z3; and germ line. Is an ortholog of human KIF15 (kinesin family member 15). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C06G3.2 | |||||
Corresponding_transcript | C06G3.2.1 | ||||||
Other_sequence | XI02457 | ||||||
OOC00018_1 | |||||||
Tcol_isotig22220 | |||||||
CJC11439_1 | |||||||
CJC03116_1 | |||||||
Associated_feature | WBsf977135 | ||||||
WBsf977136 | |||||||
WBsf977137 | |||||||
WBsf977138 | |||||||
WBsf996872 | |||||||
WBsf1017643 | |||||||
WBsf228493 | |||||||
WBsf228494 | |||||||
Experimental_info | RNAi_result (23) | ||||||
Expr_pattern | Expr2631 | ||||||
Expr2632 | |||||||
Expr1010889 | |||||||
Expr1031305 | |||||||
Expr1144008 | |||||||
Expr2012961 | |||||||
Expr2031193 | |||||||
Drives_construct | WBCnstr00036371 | ||||||
Construct_product | WBCnstr00036371 | ||||||
Antibody | WBAntibody00000693 | ||||||
WBAntibody00000694 | |||||||
Microarray_results (31) | |||||||
Expression_cluster (175) | |||||||
Interaction (27) | |||||||
Map_info | Map | IV | Position | 3.2795 | Error | 0.000501 | |
Positive | Positive_clone | C06G3 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Pseudo_map_position | |||||||
Reference (25) | |||||||
Remark | Sequence connection from [Siddiqui SS], [krb 020711] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |