WormBase Tree Display for Gene: WBGene00002257
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| WBGene00002257 | SMap | S_parent | Sequence | W02D3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lbp-5 | Person_evidence | WBPerson492 | |||||
| Sequence_name | W02D3.7 | ||||||||
| Molecular_name | W02D3.7 | ||||||||
| W02D3.7.1 | |||||||||
| CE14430 | |||||||||
| Other_name | CELE_W02D3.7 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | lbp-5 | ||||||||
| DB_info | Database | AceView | gene | 1H308 | |||||
| WormQTL | gene | WBGene00002257 | |||||||
| WormFlux | gene | WBGene00002257 | |||||||
| NDB | locus_tag | CELE_W02D3.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002257|UniProtKB=O01814 | |||||||
| family | PTHR11955 | ||||||||
| NCBI | gene | 191700 | |||||||
| RefSeq | protein | NM_059527.6 | |||||||
| SwissProt | UniProtAcc | O01814 | |||||||
| UniProt_GCRP | UniProtAcc | O01814 | |||||||
| OMIM | gene | 170715 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lbp | ||||||||
| Allele (11) | |||||||||
| Strain | WBStrain00055607 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00025802 | ||||||||
| 00025803 | |||||||||
| 00025804 | |||||||||
| 00025805 | |||||||||
| 00025806 | |||||||||
| 00025807 | |||||||||
| 00025808 | |||||||||
| 00025809 | |||||||||
| 00110322 | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00002253 | ||||||||
| WBGene00002254 | |||||||||
| WBGene00002255 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00002256 | |||||||||
| WBGene00002259 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00002258 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00002260 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00021486 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | lbp-5 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-5 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; loss of lbp-5 activity via large-scale RNAi screens indicates that, in C. elegans, LBP-5 is required for movement. | Paper_evidence | WBPaper00003911 | |||||
| WBPaper00004402 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables fatty acid binding activity. Predicted to be involved in fatty acid transport. Located in nucleus and perinuclear region of cytoplasm. Expressed in hypodermis and tail. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1G; glioblastoma; and pre-eclampsia. Is an ortholog of several human genes including FABP4 (fatty acid binding protein 4); FABP7 (fatty acid binding protein 7); and PMP2 (peripheral myelin protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3562) | ||||
| DOID:0111560 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9117) | ||||||
| DOID:10591 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3559) | ||||||
| Molecular_info | Corresponding_CDS | W02D3.7 | |||||||
| Corresponding_transcript | W02D3.7.1 | ||||||||
| Other_sequence (16) | |||||||||
| Associated_feature | WBsf219627 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00066088 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00102246 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00088958 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00054592 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036187 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00102646 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116837 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004376 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1868 | ||||||||
| Chronogram1902 | |||||||||
| Chronogram1961 | |||||||||
| Expr6825 | |||||||||
| Expr9583 | |||||||||
| Expr1027724 | |||||||||
| Expr1158136 | |||||||||
| Expr2013022 | |||||||||
| Expr2031254 | |||||||||
| Drives_construct | WBCnstr00003577 | ||||||||
| WBCnstr00008795 | |||||||||
| WBCnstr00014148 | |||||||||
| WBCnstr00036354 | |||||||||
| Construct_product | WBCnstr00008795 | ||||||||
| WBCnstr00014148 | |||||||||
| WBCnstr00036354 | |||||||||
| Regulate_expr_cluster | WBPaper00044427:lbp-5(tm1618)_downregulated | ||||||||
| WBPaper00044427:lbp-5(tm1618)_upregulated | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (238) | |||||||||
| Interaction (37) | |||||||||
| Map_info | Map | I | Position | 1.30111 | Error | 0.000265 | |||
| Positive | Positive_clone | W02D3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4956 | |||||||
| 5560 | |||||||||
| Reference (15) | |||||||||
| Method | Gene |
