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WormBase Tree Display for Gene: WBGene00002985

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Name Class

WBGene00002985EvidenceCGC_data_submission
SMapS_parentSequenceC29A12
IdentityVersion1
NameCGC_namelig-1Person_evidenceWBPerson1551
Sequence_nameC29A12.3
Molecular_nameC29A12.3a
C29A12.3a.1
CE37480
C29A12.3b
CE37481
C29A12.3b.1
Other_nameCELE_C29A12.3Accession_evidenceNDBBX284605
Public_namelig-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlig
Allele (34)
RNASeq_FPKM (74)
GO_annotation (25)
Ortholog (39)
ParalogWBGene00010626Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002986Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022237Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionlig-1 encodes a putative ATP-dependent DNA ligase, based on homology; lig-1 may be one of the direct targets of the daf-16 forkhead transcription factor, based on chromatin immunoprecipitation (ChIP) studies.Paper_evidenceWBPaper00027009
Curator_confirmedWBPerson324
WBPerson1823
WBPerson567
Date_last_updated19 Feb 2013 00:00:00
Automated_descriptionPredicted to enable DNA ligase (ATP) activity. Predicted to be involved in DNA ligation and Okazaki fragment processing involved in mitotic DNA replication. Predicted to be located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in inherited metabolic disorder and primary immunodeficiency disease. Is an ortholog of human LIG1 (DNA ligase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6598)
DOID:655Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6598)
Molecular_infoCorresponding_CDSC29A12.3a
C29A12.3b
Corresponding_CDS_historyC29A12.3:wp49
C29A12.3a:wp132
C29A12.3b:wp132
Corresponding_transcriptC29A12.3a.1
C29A12.3b.1
Other_sequence (56)
Associated_featureWBsf647199
WBsf1001198
WBsf1001199
WBsf1001200
WBsf1001201
WBsf1020354
WBsf1020355
WBsf232421
Experimental_infoRNAi_resultWBRNAi00071564Inferred_automaticallyRNAi_primary
WBRNAi00041439Inferred_automaticallyRNAi_primary
WBRNAi00110407Inferred_automaticallyRNAi_primary
WBRNAi00007593Inferred_automaticallyRNAi_primary
WBRNAi00078459Inferred_automaticallyRNAi_primary
WBRNAi00024665Inferred_automaticallyRNAi_primary
WBRNAi00110406Inferred_automaticallyRNAi_primary
WBRNAi00078941Inferred_automaticallyRNAi_primary
WBRNAi00008458Inferred_automaticallyRNAi_primary
WBRNAi00110405Inferred_automaticallyRNAi_primary
Expr_patternExpr1019333
Expr1031384
Expr1145468
Expr2013149
Expr2031381
Drives_constructWBCnstr00036305
Construct_productWBCnstr00036305
Microarray_results (26)
Expression_cluster (163)
Interaction (248)
Map_infoMapVPosition2.81975Error0.001231
PositivePositive_cloneC29A12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005654
WBPaper00005745
WBPaper00026722
WBPaper00027009
WBPaper00038491
WBPaper00048493
WBPaper00055090
WBPaper00065149
RemarkSequence connection from [Boulton S, Vidal M]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene