WormBase Tree Display for Gene: WBGene00003173
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WBGene00003173 | SMap | S_parent | Sequence | C50H2 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | mec | ||||||
Allele (119) | |||||||
Legacy_information | u27amber : touch insensitive lethargic. ES2 ME2. NA > 20 (e1494 u164amber etc.). | ||||||
[C.elegansII] u27amb : touch insensitive lethargic. ES2 ME2. OA>30: e1494, e1852, u164amb etc. Cloned: 2 kb and 3 kb transcripts, transpliced to SL1 and SL2, encode protein with Kunitztype serine protease inhibitor domains, EGF-like repeats. mec-9:GFP expressed in touch cells and PVD (3kb promoter) or more extensively (2kb promoter). [Chalfie and Au 1989; Huang and Chalfie 1994; TU] | |||||||
Strain | WBStrain00032822 | ||||||
WBStrain00004348 | |||||||
WBStrain00006234 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (21) | |||||||
Paralog (31) | |||||||
Structured_description | Concise_description | mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons. | Paper_evidence | WBPaper00002379 | |||
WBPaper00005666 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable calcium ion binding activity and serine-type endopeptidase inhibitor activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Predicted to be located in extracellular region. Expressed in PVDL; PVDR; head neurons; touch receptor neurons; and ventral cord neurons. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C50H2.3a | |||||
C50H2.3b | |||||||
Corresponding_CDS_history | C50H2.3a:wp144 | ||||||
C50H2.3b:wp144 | |||||||
Corresponding_transcript | C50H2.3a.1 | ||||||
C50H2.3b.1 | |||||||
Other_sequence (14) | |||||||
Associated_feature | WBsf669266 | ||||||
WBsf669267 | |||||||
WBsf669268 | |||||||
WBsf1001008 | |||||||
WBsf1020239 | |||||||
WBsf234297 | |||||||
Experimental_info | RNAi_result | WBRNAi00042982 | Inferred_automatically | RNAi_primary | |||
WBRNAi00012263 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00067621 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00112683 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089014 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr268 | ||||||
Expr1026433 | |||||||
Expr1146947 | |||||||
Expr2013503 | |||||||
Expr2031737 | |||||||
Drives_construct (2) | |||||||
Construct_product | WBCnstr00036197 | ||||||
Microarray_results (23) | |||||||
Expression_cluster (161) | |||||||
Interaction (29) | |||||||
Map_info | Map | V | Position | 2.2108 | Error | 0.000399 | |
Well_ordered | |||||||
Positive | Inside_rearr | eDf1 | |||||
Positive_clone | C50H2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Negative | Negative_clone | F15H4 | |||||
Mapping_data | 2_point | 133 | |||||
Multi_point | 284 | ||||||
3103 | |||||||
3104 | |||||||
4628 | |||||||
Pos_neg_data | 495 | ||||||
1747 | |||||||
1751 | |||||||
3124 | |||||||
3125 | |||||||
3126 | |||||||
3127 | |||||||
Reference (49) | |||||||
Method | Gene |