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WormBase Tree Display for Gene: WBGene00003308

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Name Class

WBGene00003308EvidencePaper_evidenceWBPaper00004928
SMapS_parentSequenceK01F9
IdentityVersion2
NameCGC_namemir-80Person_evidenceWBPerson18
Sequence_nameK01F9.3
Molecular_nameK01F9.3
K01F9.3a
K01F9.3b
Other_namemir-227Person_evidenceWBPerson18
cel-mir-80RemarkmiRBase V21 import
Cel-Bantam-P2RemarkMirGeneDB 2.1 import
CELE_K01F9.3Accession_evidenceNDBBX284603
Public_namemir-80
DB_infoDatabasemiRBaseaccMI0000051
SignaLinkmirnacel-mir-80
MirGeneDBcelCel-Bantam-P2
NDBlocus_tagCELE_K01F9.3
NCBIgene3565575
RefSeqproteinNR_002370.2
RNAcentralURSidURS00000625AC
URS00005C06A7
URS00005C93DF
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
206 Jun 2007 09:09:48WBPerson2970EventAcquires_mergeWBGene00003320
Name_changeOther_namemir-227
Acquires_mergeWBGene00003320
StatusLive
Gene_infoBiotypeSO:0001265
Gene_classmir
Allele (12)
StrainWBStrain00027443
WBStrain00007203
WBStrain00007204
WBStrain00007206
In_clusterBANTAM
RNASeq_FPKM (74)
GO_annotation00106254
Structured_descriptionConcise_descriptionmir-80 encodes a microRNA, a small non-protein coding RNA and is conserved in C. briggsae; based on RNA sequence the mir-80 family also includes C. elegans miR-81 and miR-82 and human miR-143; mir-80 is strongly expressed at all developmental stages in normal worms and in glp-4(bn2) mutant worms; many of the known microRNAs are involved in post-transcriptional regulation of genes; the precise function of miR-80 is unknown.Paper_evidenceWBPaper00004927
WBPaper00004928
WBPaper00005825
Curator_confirmedWBPerson324
Date_last_updated08 Feb 2005 00:00:00
Automated_descriptionInvolved in regulation of gene expression. Expressed in excretory cell; hypodermis; pharynx; somatic nervous system; and tail neurons. Used to study Parkinson's disease.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:14330Homo sapiensPaper_evidenceWBPaper00035654
Curator_confirmedWBPerson324
Date_last_updated06 Jan 2014 00:00:00
Disease_relevancemir-80 is a small non-protein coding RNA; microRNA expression profiling studies in an elegans transgenic model of Parkinson''s disease, where A53T alpha-synuclein is overexpressed, indicate that elegans mir-80 is differentially expressed.Homo sapiensPaper_evidenceWBPaper00035654
Curator_confirmedWBPerson324
Date_last_updated06 Jan 2014 00:00:00
Models_disease_in_annotationWBDOannot00000266
Molecular_infoCorresponding_transcriptK01F9.3
K01F9.3a
K01F9.3b
Other_sequenceAJ487603
Associated_featureWBsf979111
WBsf993492
WBsf1015500
Gene_product_bindsWBsf977969
WBsf977970
WBsf977971
WBsf977972
Experimental_infoExpr_patternExpr1671
Expr2498
Expr8413
Expr10928
Expr11257
Drives_constructWBCnstr00005494
WBCnstr00005535
WBCnstr00018399
Expression_cluster (34)
Interaction (14)
Map_infoPositiveInside_rearrnDf53
Positive_cloneK01F9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataPos_neg_data10923
Interpolated_map_positionIII-0.0387588
Reference (20)
RemarkThis mir gene has a paired gene (mir-227) encoded on the either side of the stemloop structure. I.e. both genes undergo base pairing with each other in the formation of the stem-loop. [040701 krb]
MethodGene