WormBase Tree Display for Gene: WBGene00003352

WBGene00003352 Evidence: Paper_evidence: WBPaper00005879
  SMap: S_parent: Sequence: AC8
  Identity: Version: 3
    Name: CGC_name: mir-258.1 Person_evidence: WBPerson18
      Sequence_name: AC8.8
      Molecular_name: AC8.8
        AC8.8a
      Other_name: mir-258 CGC_data_submission
        mir-258-1 Accession_evidence: MI0000335
        cel-mir-258a Remark: miRBase V21 import
        mir-258a Remark: miRBase V21 import
        CELE_AC8.8 Accession_evidence: NDB BX284606
      Public_name: mir-258.1
    DB_info: Database: miRBase acc MI0000335
        NDB locus_tag CELE_AC8.8
        NCBI gene 3565828
        RefSeq protein NR_002410.2
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:31 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 09 Nov 2004 10:51:56 WBPerson2970 Name_change: CGC_name: mir-258.1
        3 22 Feb 2010 13:26:12 WBPerson2970 Name_change: Other_name: mir-258-1
    Status: Live
  Gene_info: Biotype: SO:0001265
    Gene_class: mir
    Allele (14)
    RNASeq_FPKM (74)
    Structured_description: Concise_description: mir-258.1 encodes a microRNA, a small non-protein coding RNA; there are two copies of mir-258 in the genome: mir-258.1 and mir-258.2; mir-258.1 is uniformly expressed from the embryonic stage to the adult stage; many of the known microRNAs are involved in post-transcriptional regulation of genes; the precise function of miR-258.1 is unknown. Paper_evidence: WBPaper00005879
          Curator_confirmed: WBPerson324
          Date_last_updated: 16 Jul 2007 00:00:00
      Automated_description: Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_transcript: AC8.8
      AC8.8a
    Associated_feature: WBsf979150
  Experimental_info: Expr_pattern: Expr8435
    Drives_construct: WBCnstr00013302
    Expression_cluster: WBPaper00042480:20mM_nicotine_upregulated
      WBPaper00048474:SpaceRadiation_downregulated_N2
      WBPaper00051404:alg-1(gk214)_downregulated_miRNA
      WBPaper00051404:alg-2(ok304)_upregulated_miRNA
      WBPaper00051404:alg-5(ram2)_downregulated_miRNA
      WBPaper00051404:alg-5(tm1163)_upregulated_miRNA
      WBPaper00061613:human-amyloid-beta_upregulated
    Interaction: WBInteraction000542162
  Map_info: Map: X Position: -20.2369 Error: 0.035776
    Positive: Positive_clone: AC8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005879
    WBPaper00031335
    WBPaper00058742
  Remark: There are 2 copies of mir-258 in the genome. The gene now named mir-258.1 was the first copy characterised and was known as mir-258 Curator_confirmed: WBPerson2970
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    The annotation of cel-mir-258 as a microRNA was questioned by Jan et al (Nature 2011 469:97-101). The pattern of reads from deep sequencing datasets aggregated in miRBase and mapping to the locus is not consistent with microRNA processing. The sequence is removed from miRBase 21.
  Method: Gene