WormBase Tree Display for Gene: WBGene00003403
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| WBGene00003403 | Evidence | Paper_evidence | WBPaper00005801 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C29F5 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | mps-1 | Person_evidence | WBPerson145 | |||||
| Sequence_name | C29F5.4 | ||||||||
| Molecular_name | C29F5.4 | ||||||||
| C29F5.4.1 | |||||||||
| CE33602 | |||||||||
| Other_name | CELE_C29F5.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | mps-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00003403 | |||||
| WormFlux | gene | WBGene00003403 | |||||||
| NDB | locus_tag | CELE_C29F5.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003403|UniProtKB=Q27GU3 | |||||||
| family | PTHR12876 | ||||||||
| NCBI | gene | 183012 | |||||||
| RefSeq | protein | NM_062862.5 | |||||||
| TREEFAM | TREEFAM_ID | TF316798 | |||||||
| TrEMBL | UniProtAcc | Q27GU3 | |||||||
| UniProt_GCRP | UniProtAcc | Q27GU3 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mps | ||||||||
| Allele (23) | |||||||||
| Strain | WBStrain00036199 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (21) | |||||||||
| Paralog | WBGene00020482 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mps-1 encodes single-pass transmembrane proteins that are related to the vertebrate KCNE proteins, also known as MinK-related peptides (MiRPs) that associate with, and regulate, pore-forming ion channels; mps-1 is required for the normal function of several neurons and thus for normal body touch sensation, chemotaxis to select molecules, osmotic avoidance, and nose-touch; when assayed in ASER neurons or in tissue culture cells coexpressing C. elegans KVS-1, MPS-1 is able to alter the activity of this potassium-selective channel, suggesting that MPS-1 functions in vivo to regulate KVS-1 activity in neurons in which the two proteins are coexpressed; mps-1 reporter fusions are expressed in the vulva and in several chemosensory and mechanosensory neurons, including the ADF neuron. | Paper_evidence | WBPaper00005801 | |||||
| WBPaper00025063 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 May 2007 00:00:00 | ||||||||
| Automated_description | Enables potassium channel regulator activity and protein serine/threonine kinase activity. Involved in several processes, including hyperosmotic response; mechanosensory behavior; and negative regulation of potassium ion transport. Located in axolemma; dendrite membrane; and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Expressed in amphid neurons; touch receptor neurons; and vulva. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C29F5.4 | |||||||
| Corresponding_CDS_history | C29F5.4:wp97 | ||||||||
| C29F5.4:wp155 | |||||||||
| C29F5.4b:wp227 | |||||||||
| Corresponding_transcript | C29F5.4.1 | ||||||||
| Other_sequence | NB09438 | ||||||||
| NBC06242_1 | |||||||||
| MC02393 | |||||||||
| HG01115 | |||||||||
| HGC05280_1 | |||||||||
| MCC01040_1 | |||||||||
| Associated_feature | WBsf988124 | ||||||||
| WBsf988125 | |||||||||
| WBsf988126 | |||||||||
| WBsf223147 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr2317 | ||||||||
| Expr2453 | |||||||||
| Expr12627 | |||||||||
| Expr1026033 | |||||||||
| Expr1145502 | |||||||||
| Expr2013671 | |||||||||
| Expr2031905 | |||||||||
| Drives_construct | WBCnstr00005687 | ||||||||
| WBCnstr00005688 | |||||||||
| WBCnstr00005689 | |||||||||
| WBCnstr00005690 | |||||||||
| WBCnstr00005691 | |||||||||
| WBCnstr00005692 | |||||||||
| WBCnstr00010765 | |||||||||
| WBCnstr00010842 | |||||||||
| WBCnstr00019864 | |||||||||
| Construct_product | WBCnstr00005687 | ||||||||
| WBCnstr00005688 | |||||||||
| WBCnstr00005689 | |||||||||
| WBCnstr00005690 | |||||||||
| WBCnstr00005691 | |||||||||
| WBCnstr00005692 | |||||||||
| WBCnstr00019864 | |||||||||
| Microarray_results (15) | |||||||||
| Expression_cluster (94) | |||||||||
| Interaction (35) | |||||||||
| Map_info | Map | II | Position | -0.387718 | Error | 0.000675 | |||
| Positive | Positive_clone | C29F5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5134 | |||||||
| 5077 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005801 | ||||||||
| WBPaper00025063 | |||||||||
| WBPaper00026859 | |||||||||
| WBPaper00028450 | |||||||||
| WBPaper00029017 | |||||||||
| WBPaper00030824 | |||||||||
| WBPaper00033024 | |||||||||
| WBPaper00033073 | |||||||||
| WBPaper00045936 | |||||||||
| WBPaper00052591 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
