WormBase Tree Display for Gene: WBGene00003587
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| WBGene00003587 | SMap | S_parent | Sequence | F45H11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ned-8 | Person_evidence | WBPerson89 | |||||
| Sequence_name | F45H11.2 | ||||||||
| Molecular_name | F45H11.2 | ||||||||
| F45H11.2.1 | |||||||||
| CE10552 | |||||||||
| Other_name | CELE_F45H11.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ned-8 | ||||||||
| DB_info | Database | AceView | gene | 1K950 | |||||
| WormQTL | gene | WBGene00003587 | |||||||
| WormFlux | gene | WBGene00003587 | |||||||
| NDB | locus_tag | CELE_F45H11.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003587|UniProtKB=Q93725 | |||||||
| family | PTHR10666 | ||||||||
| NCBI | gene | 172910 | |||||||
| RefSeq | protein | NM_001392929.1 | |||||||
| SwissProt | UniProtAcc | Q93725 | |||||||
| TREEFAM | TREEFAM_ID | TF300072 | |||||||
| UniProt_GCRP | UniProtAcc | Q93725 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ned | ||||||||
| Allele (12) | |||||||||
| Strain | WBStrain00037754 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (23) | |||||||||
| Paralog | WBGene00006727 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00018660 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00018659 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00006725 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018661 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00006728 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | The ned-8 gene encodes a ubiquitin-like protein that is required for both embryogenesis and terminal hypodermal differentiation. | Paper_evidence | WBPaper00004363 | |||||
| WBPaper00005108 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of gene expression; and regulation of apoptotic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease and malignant astrocytoma. Is an ortholog of human NEDD8 (NEDD8 ubiquitin like modifier). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:14330 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7732) | ||||
| DOID:3069 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7732) | ||||||
| Molecular_info | Corresponding_CDS | F45H11.2 | |||||||
| Corresponding_transcript | F45H11.2.1 | ||||||||
| Other_sequence (98) | |||||||||
| Associated_feature | WBsf649570 | ||||||||
| WBsf655313 | |||||||||
| WBsf664860 | |||||||||
| WBsf664861 | |||||||||
| WBsf984990 | |||||||||
| WBsf220232 | |||||||||
| Experimental_info | RNAi_result (27) | ||||||||
| Expr_pattern | Expr1064 | ||||||||
| Expr2678 | |||||||||
| Expr1010794 | |||||||||
| Expr1031637 | |||||||||
| Expr1151290 | |||||||||
| Expr2013950 | |||||||||
| Expr2032189 | |||||||||
| Drives_construct | WBCnstr00036023 | ||||||||
| Construct_product | WBCnstr00036023 | ||||||||
| Antibody | WBAntibody00000319 | ||||||||
| WBAntibody00000454 | |||||||||
| WBAntibody00000666 | |||||||||
| WBAntibody00001633 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (107) | |||||||||
| Interaction (92) | |||||||||
| Map_info | Map | I | Position | 4.94399 | Error | 0.003231 | |||
| Positive | Positive_clone | F45H11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
